Employing mesenchymal stem cells to support tumor-targeted
2018年1月25日 · In more aggressive HER2-amplified HCC-1954 cells, HCC-379 and HCC-NTC tumor growth rate in vivo was similar, but increased tumor necrosis was observed in HCC-379 …
Loss of SGK1 supports metastatic colonization in hepatocellular ...
2025年1月30日 · SGK1 expression in metastases predict response to immune checkpoint inhibitors. Immune evasion by tumor cells is a principal obstacle to effectively targeting …
SPINK1-induced tumor plasticity provides a therapeutic window …
2023年11月29日 · Our recent study identified CD133/Prom1 in hepatocellular carcinoma (HCC) tumors to mark proliferative tumor-propagating cells with cancer stem cell-like properties, that …
Employing mesenchymal stem cells to support tumor-targeted
A significant reduction in the rate of tumor formation and growth in vivo was observed in T47D breast cancer cells stably expressing miR-379. In more aggressive HER2-amplified HCC-1954 …
Cell子刊：王红阳院士团队发现肝癌的新型防护因子——LTA4H_澎 …
2025年3月9日 · 肝细胞癌（hcc）是最常见的原发性肝癌，是全球第六大常见的癌症和第三大癌症相关死亡原因。许多患者确诊时已处于晚期，限制了根治性疗法的选择，导致预后不良，其特 …
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC ... - Nature
2024年11月22日 · Here, we identified SZT2-AS1 as a novel lncRNA in HCC, which was induced by hypoxia in a HIF-1-dependent manner and promoted HCC growth, metastasis and …
S100A10 promotes HCC development and progression via transfer …
Neutralising antibody (NA) to S100A10 was used to evaluate the significance of EV-S100A10. Functionally, S100A10 promoted HCC initiation, self-renewal, chemoresistance and …
Abstract 3045: Engineering Mesenchymal Stem Cells (MSCs) to …
2017年7月1日 · HCC1954 breast cancer cells were transduced with lentivirus to express elevated miR-379 (HCC-379) or a control sequence (HCC-NTC). Cells were implanted into the …
Nuclear-localized HKDC1 promotes hepatocellular carcinoma …
Here, we demonstrate that nuclear-localized HKDC1 acts as a protein kinase to promote hepatocellular carcinoma (HCC) cell proliferation. Mechanistically, HKDC1 phosphorylates RB …
赵宏团队：重建HBV整合基因图谱，揭示肝细胞癌促发机制
2024年3月9日 · 进一步比较TCGA HCC样本 （n=361） 中HBsAg阳性组 （n=106） 和HBsAg阴性组 （n=245） 的拷贝数变异 （CNVs） ，以研究HBV诱导的CNVs在HBV+HCC中是否过度表 …
- 某些结果已被删除