Dehydration entropy drives liquid-liquid phase separation by …
2020年6月26日 · Experimental and field-theoretic simulation results are consistent with PEG driving LLPS by dehydration of polymers, and show that PEG exerts its effect without …
Intermolecular interactions underlie protein/peptide phase
2023年10月4日 · Liquid-liquid phase separation (LLPS) has emerged as a crucial biological phenomenon underlying the sequestration of macromolecules (such as proteins and nucleic...
『珍藏版』Cell发布“相分离”研究指南 - 知乎
LLPS的发生，高度依赖溶液中生物大分子（比如：蛋白，DNA以及RNA等）的浓度、物理化学性质，以及溶液所处的环境，比如：温度、pH、盐离子浓度、盐离子类型以及溶液中存在其它 …
Non-associative phase separation in an evaporating droplet as ... - Nature
2021年5月27日 · LLPS is a thermodynamically transient, nonequilibrium process leading to phase segregation (nonassociative or segregative phase separation) or the formation of coacervates...
Liquid–Liquid Phase-Separated Systems from Reversible Gel–Sol ...
2021年7月8日 · An LLPS system from the gel–sol transition of protein (gelatin solution) in a macromolecular crowding agent (PEG solution). a) Schematics and microscopy images of the …
技术专题 | 液-液相分离 (LLPS)：现代生物医学中的新前沿【珍藏】 …
液-液相分离（Liquid-Liquid Phase Separation, LLPS）是指在细胞内某些生物大分子（如蛋白质和RNA）通过相互作用，形成具有不同组分和性质的相分离液滴 [1]。 这些液滴类似于油滴在水 …
Liquid–liquid phase separation in aqueous solutions of …
2021年7月14日 · Here, to the best of our knowledge, we report for the first time LLPS in concentrated aqueous solutions of PEG-based methacrylate homopolymers and their mixtures …
Role of PEG in liquid-liquid phase separation of proteins in vitro a ...
Liquid-liquid phase separation (LLPS) has emerged as a crucial biological phenomenon underlying the sequestration of macromolecules (such as proteins and...
Liquid–liquid phase separation (LLPS) can be used as a direct tool for probing both protein–protein and protein–PEG inter-actions. It has been shown that the position of the …
Liquid-liquid phase separation: Fundamental physical principles ...
2023年12月1日 · This review offers a concise overview of LLPS in soft matter, emphasizing its relevance in soft material engineering. We delve into fundamental mechanisms, focusing on …