PLGF-based testing to help diagnose suspected preterm pre …
2022年7月27日 · Evidence-based recommendations on placental growth factor (PLGF)-based testing to help diagnose suspected preterm pre-eclampsia. The tests are: DELFIA Xpress PLGF 1 2 3, DELFIA Xpress sFlt 1/PLGF 1 2 3 ratio, Elecsys immunoassay sFlt …
High-quality evidence now shows that this test, and the DELFIA Xpress sFlt-1/PLGF 1-2-3 ratio assay, have good accuracy for preterm pre-eclampsia. NICE previously recommended the Elecsys immunoassay sFlt-1/PLGF ratio and Triage PLGF Test to help rule out pre-eclampsia.
PlGF-based testing to help diagnose suspected pre-eclampsia
2016年5月11日 · PlGF-based testing to help diagnose suspected pre-eclampsia (Triage PlGF test, Elecsys immunoassay sFlt-1/PlGF ratio, DELFIA Xpress PlGF 1-2-3 test, and BRAHMS …
Clinical utility of sFlt‐1 and PlGF in screening, prediction, diagnosis ...
2022年7月11日 · In this Review, we summarize the existing knowledge, examining the performance of maternal PlGF, sFlt-1 and the sFlt-1/PlGF ratio for screening PE, predicting development of PE in the short term, diagnosing PE, monitoring established PE and predicting other placenta-related disorders in singleton pregnancy.
Placental growth factor testing for pre-eclampsia - PMC
It has been shown that in women with suspected pre-eclampsia, low circulating maternal PlGF concentrations (<5th centile or ≤ 100 pg/ml) have a high sensitivity (96%; 95% CI 89–99) and negative predictive value (98%; 93–99·5) in diagnosing pre …
Placental growth factor in suspected preterm pre-eclampsia: a …
2020年7月23日 · Angiogenic biomarkers, including placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFlt-1), have been identified as valuable biomarkers for preterm pre-eclampsia, accelerating diagnosis and reducing maternal adverse outcomes by risk stratification, with enhanced surveillance for high-risk women.
A new blood test (known as PLGF based tests) indicates whether the women has the disease and when used in women with suspected pre-eclampsia can reliably indicate who will need delivery soon. It is a reliable test of whether the baby is at risk.
Placental growth factor and pre-eclampsia - PMC
Placental growth factor (PlGF) is an increasingly important player in the clinical management of pre-eclampsia. This review outlines the role of PlGF in human physiology but focuses specifically on the current understanding of PlGF’s function in …
Placental growth factor testing to assess women with suspected …
Our stepped-wedge cluster-randomised controlled trial provides evidence of the clinical effects of PlGF-based testing on the time to diagnosis and maternal and perinatal outcomes in women with suspected pre-eclampsia.
DELFIA Xpress PlGF 1-2-3 is intended for the quantitative determination of PlGF in maternal serum using the 6000 ELFIA® Xpress clinical random access screening platform. The kit is described as being an aid in screening pregnant women for pre-eclampsia in all trimesters of preg