Angiotensin receptor blockers (also called ARBs or angiotensin II inhibitors) are medicines that dilate (widen) blood vessels, and are used in the treatment of conditions such as high blood pressure (hypertension), heart failure, or kidney disease in people with diabetes. ARBs work by blocking the action of a natural chemical called angiotensin II.

All national guidelines for the management of hypertension recommend angiotensin receptor blockers (ARBs) as an initial or add-on antihypertensive therapy. The 8 available ARBs have variable clinical efficacy when used for control of hypertension.

2023年5月24日 · 血管紧张素受体拮抗剂（arb）在高血压治疗中有着重要的地位。 ARB 类药物的品种繁多，常以「沙坦」命名，目前临床上可见到的沙坦类药物，看似大同小异，但却各有不同。

2023年3月27日 · As a class, angiotensin receptor blockers, or ARBs, bind to and inhibit the angiotensin II type 1 receptor and are indicated to treat hypertension, congestive heart failure, and diabetic nephropathy. They are often used as an ACE inhibitor therapy replacement for patients who cannot tolerate ACE inhibitors because of the ACE inhibitor-induced ...

2024年2月28日 · 沙库巴曲缬沙坦是全球首个血管紧张素受体脑啡肽酶抑制剂（ARNI）类药物，缬沙坦与脑啡肽酶抑制剂合用，通过降解多种影响血压的肽物质来降低血压、降低醛固酮水平、抑制心肌纤维化、防止心肌的肥厚对抗心衰，降低心血管死亡和心力衰竭住院风险。 已有大量的循证医学证据证明其在治疗心衰和高血压方面疗效确切且具有良好的安全性，也成为心衰治疗中的“新宠”。 推荐ARB＋利尿剂或ARB＋CCB四周后血压仍不达标者，可增加ARB、CCB或利尿剂的用 …

arb是最常用的高血压一线治疗药物之一。arb通过选择性阻断血管紧张素Ⅱ受体（at1型）,阻断了血管紧张素Ⅱ(angⅡ)收缩血管、升高血压、促进醛固酮分泌、水钠潴留、交感神经兴奋等作用，产生与血管紧张素转换酶抑制剂(acei)相似的药理学作用。

Over the last two decades, several angiotensin II receptor blockers (ARBs; eg, losartan, valsartan, telmisartan, olmesartan) have been approved as antihypertensive therapies. 11 ARBs provide clinically meaningful benefits for patients with cardiovascular and/or renal disease, 11 and ARBs generally have better tolerability profiles than ACE inhib...

血管紧张素II受体拮抗剂（Angiotensin II receptor antagonist），也被称为血管紧张素受体阻滞剂（angiotensin receptor blockers, ARBs)或AT 1 受体拮抗剂，是一类作用于肾素-血管紧张素系统的药物。

The renin-angiotensin-aldosterone system plays an important role in the pathophysiology of hypertension and is closely related with cardio- and cerebrovascular events and chronic kidney diseases. Each angiotensin receptor blocker (ARB) is important in the treatment of hypertension, according to the …

2023年3月27日 · This activity reviews the indications, contraindications, activity, adverse events, and other key elements of ARB therapy in the clinical setting related to the essential points needed by members of an interprofessional team managing the care of patients with hypertension and its related conditions and sequelae.