Advanced safety, hybrid electrification, and countless innovations let the GLS 450 respond to your voice, and to your desires now and tomorrow. Explore the GLS 450 SUV, including specifications, key features, packages and more. Then browse inventory or schedule a test drive.

Search from 1868 Used Mercedes-Benz GLS 450 cars for sale, including a 2017 Mercedes-Benz GLS 450 4MATIC, a 2019 Mercedes-Benz GLS 450 4MATIC, and a 2020 Mercedes-Benz GLS 450 4MATIC ranging in price from $10,500 to $100,815.

Anyone accustomed to S-class luxury but needing more space or ground clearance will feel right at home in the three-row GLS-class SUV. It offers a pair of engines—a 375-hp turbocharged inline-six...

The 2025 Mercedes-Benz GLS is a three-row SUV that seats up to seven passengers and is available in three trims: GLS 450, GLS 580 and AMG GLS 63. Each includes a generous list of standard...

Both the 375-hp GLS 450 turbo inline-6 and the GLS 580's 510-hp biturbo V8 offer advanced tech and abundant torque. Featuring hybrid electrification, their Integrated Starter-Generator can also add 20 hp, or allow gas-free coasting and lower emissions.

Customize your 2025 GLS 450 4MATIC SUV. Choose the color, wheels, interior, accessories and more. View pricing, save your build, or search for inventory.

The three-row GLS-class pairs a first-class cabin with silky powertrains, topping it off with a comfortable ride and easygoing handling.