2023年7月25日 · Lenalidomide and dexamethasone with bortezomib (VRd) or carfilzomib (KRd) are commonly used induction regimens in the U.S. This single-center, retrospective study evaluated outcomes and...

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2023年7月25日 · Lenalidomide and dexamethasone with bortezomib (VRd) or carfilzomib (KRd) are commonly used induction regimens in the U.S. This single-center, retrospective study evaluated outcomes and safety of VRd and KRd. Primary …

2025年3月14日 · A real-world analysis of the carfilzomib (Kyprolis), lenalidomide (Revlimid), and dexamethasone scheme (KRd) found that the regimen led to positive efficacy and a safety profile comparable to what was seen in clinical trials in patients with relapsed or refractory multiple myeloma, according to findings from the retrospective, observational ...

2022年10月7日 · I'm having issues running Kaspersky Rescue Disk properly in my Lenovo IdeaPad 5 15 ARE05. I'll leave the exact steps I did and what results I got, with screenshots and photos along the way. 1- Downloaded the KRD ISO file from the official website.

2024年11月1日 · Factors reflecting aggressiveness of disease, such as high-risk cytogenetics at diagnosis of MM, EMD, and doubling of the M protein within 2-3 months of relapse and/or refractory status, were associated with decreased PFS and OS …

2024年10月2日 · Belantamab mafodotin-blmf (Blenrep) plus carfilzomib, lenalidomide (Revlimid), and dexamethasone (a regimen known as KRd) demonstrated early evidence of deep responses, as well as a manageable adverse event profile in previously treated patients with multiple myeloma, according to data from a phase 1 trial (NCT04822337), presented at the 21st ...

2023年1月25日 · Maintenance therapy with carfilzomib, lenalidomide, and dexamethasone led to a significant improvement in progression-free survival vs lenalidomide alone in patients with newly diagnosed multiple...

2023年8月2日 · 新一代PI卡非佐米联合来那度胺和地塞米松 (KRd)在NDMM患者中具有较高的总缓解率 (ORR)和深度、持久缓解以及可耐受的副作用，与卡非佐米相关的罕见但严重的副作用包括心血管事件。 目前仅有一项随机研究（ENDURANCE研究）在NDMM患者中比较VRd和KRd，但该研究排除了细胞遗传学高危患者和计划立即移植的患者，显示在标危NDMM中VRd和KRd之间PFS或OS无差异；高危MM中目前只有回顾性研究对比VRd和KRd方案。 尽管VRd和KRd的总 …

2022年11月15日 · The OS rate at 36 mos was 87% with KRd and 83% with KTd. MRD testing was performed in 60 pts at time of CR/VGPR. Of those, 48.3%, pts were found to be MRD neg (23.6% of the ITT population).