In U937 cells, AST has been shown to attenuate intracellular O2− production by restoring the antioxidant function of superoxide dismutase and catalase, consequently reversing ROS production and...

In LPS-sensitive U937 cells, LPS from E. coli is an agonist of TLR4. In this study, this led to a dose-dependent induction of the abovementioned inflammatory marker genes in the U937 macrophages. In addition, induction of the pro-inflammatory genes after exposure to LPS was associated with activation of NF-κB.

2021年3月24日 · Our results indicate that LPS-induced pro-inflammatory responses are enhanced by bead phagocytosis regardless of the uptake mechanism. Additionally, phagocytosis enhanced LPS-induced NF-κB...

2019年9月19日 · The production of the six detected cytokines by phorbol 12-myristate 13-acetate (PMA)-differentiated, LPS-stimulated U-937 was significantly inhibited by the kernel extracts from two cultivars Surprise and Sparrow when the extracts were added before the addition of LPS.

2014年8月22日 · In conclusion, we showed that the antioxidant SeMet inhibited LPS-induced TNF-α, NO, and PGE2 production through modulation of iNOS and COX2 gene expression in U937 human macrophage cells. Our study also showed that SeMet partially blocked LPS by inactivating the nuclear translocation of NF-κB signaling.

U937 cells were differentiated into macrophage-like cells and treated with LPS as described in the Experimental section. Cells were treated with ogipeptin A (circles), B (triangles), C (squares)...

2024年6月12日 · U-937 是应用于 生物医学 研究 的人类淋巴瘤 细胞系 [1] ，最初是从一名37岁男性患者的 组织细胞 （英语：Histiocyte） 淋巴瘤 中分离出来的 [2]，可以用于研究 单核细胞 的行为和分化。 U-937细胞因响应着多种可溶性刺激物而变得成熟及出现分化，具有成熟 巨噬细胞 的形态和特征。 U-937细胞属于髓系（Myelocyte），因此可以组成性地（例如 白介素-1 和 颗粒白血球-巨噬细胞集落刺激因子） 分泌 着大量的细胞因子和 趋化因子。 肿瘤坏死因子-α 和重组GM …

2013年11月8日 · 结论lps是活化单核巨噬细胞的重要物质,lps在高浓度时刺激巨噬细胞分泌细胞因子具 有饱和现象。 LBP本身在高浓度时具有刺激巨噬细胞的活性,低浓度的LBP能增强LPS对巨噬细胞的活化,高浓度LBP则起到负

In both U937 and THP-1 cells, LPHN1 expression levels were significantly increased (4-12-fold) by LPS, but not by LTX; when used in combination with LPS, LTX also did not significantly change...

PoodleLambAdmin May 2, 2017 March 25, 2019 Comments Off on Littlest Pet Shop #934, #935, #936, #937, #938, #939, #940, #941, #942, #974, #995