干细胞（mouse BM MSCs，mBMMSCs）通过细胞与细胞 间接触来上调PD-L1 的表达，再通过PD-1/PD-L1 通路对 成熟辅助性T（T helper，Th）17 细胞起选择性抑制作用。 MSCs 免疫调 …

2023年12月18日 · PD-L1 expression levels of WJ-MSCs could be regarded as an indicator to choose optimal MSCs for treating autoimmune disease. These findings provided novel insights …

2018年8月26日 · MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL …

In TME, mesenchymal stem cells (MSCs) play a crucial role in tumor progression, metastasis, and drug resistance. Emerging evidence suggests that MSCs can modulate the immune …

Periodontal ligament stem cells (PDLSCs), which reside in the perivascular space of the periodontium, possess characteristics of mesenchymal stem cells and are a promising tool for …

2023年5月5日 · 建议以群体倍增水平（ pdl ）定义细胞代次，或明确细胞传代过程中的群体倍增时间（ pdt ）以开展研究。 传代稳定性研究的条件应能代表实际临床/商业化生产工艺，重点关 …

尽管来自脱落乳牙（SHED），PDL-MSC和AT-MSC的MSC显示多能性标记的mRNA表达更高，但是所有MSC均表达多能性标记蛋白。 SHEDs和PDL-MSCs具有显着的成骨能力，PB-MSCs …

2021年9月29日 · Adapted from Best Practices in MSC Culture: Tracking & Reporting Cellular Age Using Population Doubling Level & Not Cell Passage Number. Is it impolite to ask an MSC its …

2019年4月15日 · Our findings demonstrated for the first time that MSC exosomes enhance periodontal regeneration possibly by increasing PDL migration and proliferation. This study …

整体计算：PDL（P5）=PDL（P0）+log2 (N5末/N1始) 。 注：“Nx始”为该步骤接种时的细胞数量，“Nx末”为该步骤培养结束时的细胞数量，“PDL（P0）”为工作细胞的PDL代次。