2022年12月10日 · ScRNAseq of the neutropenic bone marrow predicted cellular crosstalk between mature neutrophils expressing CCL6, a known chemoattractant for interferon …

2021年8月31日，四川大学华西医院生物治疗国家重点实验室魏霞蔚团队在 Cell Proliferation 上发表了题为“Role of the CCL2-CCR2 signalling axis in cancer: Mechanisms and therapeutic …

2019年11月19日 · We determined CCL6 expression in neurons and astrocytes using RT-PCR. In these experiments, CCL6 was not expressed in primary cultures of cerebral cortex neurons or …

收集野生型c57bl/6和纯合b-hccr2小鼠的骨髓，并用种属特异性抗ccr2抗体进行流式细胞术分析。 结果显示：鼠CCR2仅在野生小鼠中检测到，人CCR2仅在纯合B-hCCR2小鼠中检测到。

2024年10月1日 · Within the tumor colonies, CCR2+ nonclassical monocytes secreted CCL6 to recruit NK cells that mediated tumor regression, independent of T and B lymphocytes. Hence, …

2024年11月15日 · Within the tumor colonies, CCR2 + nonclassical monocytes secreted CCL6 to recruit NK cells that mediated tumor regression, independent of T and B lymphocytes. Hence, …

2024年7月26日 · In this study, we used single-cell RNA-sequencing analysis of Cd45 + CD11b + F4/80 + cardiac macrophages to explore the heterogeneity of cardiac macrophages. The …

Our findings reveal that mechanical force-induced functional shift of the Ccr2 macrophages cluster mediated by NF-κB pathway, leading to a pro-inflammatory response and bone remodeling. …

2021年9月21日 · We find alterations in transcriptional profiles of microglia subsets in Ccr2−/− TBI mice compared to WT TBI mice indicating that infiltrating monocytes/macrophages influence …

Using primary cortical microglial cell cultures, we observed a substantial increase in the expression of CCL2, CCL7, and CCL12 after 24 h of LPS (100 ng/mL) treatment. CCL2 …