二氢尿苷 - 维基百科，自由的百科全书
二氢尿苷（英語： Dihydrouridine ，或称为5,6-二氢尿嘧啶核苷，缩写D [1] 、DHU、UH 2 ）是一种嘧啶类核苷，由核碱基 5,6-二氢尿嘧啶与核糖通过C-N糖苷键连结而成，比常见的尿苷多了 …
Activity-based RNA-modifying enzyme probing reveals DUS3L
2021年9月23日 · We investigate the mechanism of crosslinking and use quantitative nucleoside liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis and 5-FUrd-based …
Full article: The Dihydrouridine landscape from tRNA to mRNA: a ...
The dihydrouridine (D, sometimes DHU) RNA modification is a modified pyrimidine nucleoside whose corresponding nucleobase is 5,6-dihydrouracil. D is synthesized from uridine (U) by …
Activity-based RNA modifying enzyme probing reveals DUS3L …
DHU is an abundant RNA modification found in all kingdoms of life 41-44. Yet, our understanding of this modified base in mammals is lacking. Our work provides the first transcriptome-wide …
tRNA的DHU环，TψC环与反密码环各有什么作用 ... - 知乎
D环：负责和 氨基酰tRNA聚合酶 结合。 TψC环：此臂负责和核糖体上的rRNA 识别结合。 可变环：从4 Nt到21 Nt不等，其功能是在tRNA的L型三维结构中负责连接两个区域（D环－反密码子 …
(二)转运RNA(tRNA) - drhuang.com
tRNA(transfer RNA)是蛋白质合成中的接合器分子。 tRNA分子有100多种，各可携带一种氨基酸，将其转运到核蛋白体上，供蛋白质合成使用。 tRNA是细胞内分子量最小的一类核酸， …
RNA中为什么会有T？ - 知乎
在TRNA二级结构中，从5′末端起的第一个环是DHU环，以含二氢尿嘧啶为特征；第二个环为反密码子环，其环中部的三个碱基可以与mRNA中的三联体密码子形成碱基互补配对，构成所谓的 …
The dihydrouridine (D, sometimes DHU) RNA modification is a modified pyrimidine nucleoside whose corresponding nucleo-base is 5,6-dihydrouracil. D is synthesized from uridine (U) by …
转运核糖核酸（tRNA）的结构与功能 - 哔哩 ... - 哔哩哔哩
转运核糖核酸（transfer ribonucleic acid，tRNA）是一种比较小的RNA，一般由74-93个核苷酸构成，分子量约25 kd，沉降系数4 s。在发现microRNA之前，它是最小的RNA。 tRNA的功能是 …
Entry - *621104 - DIHYDROURIDINE SYNTHASE 3-LIKE PROTEIN; …
Using RNA-mediated activity-based protein profiling, Dai et al. (2021) identified DUS3L as an RNA-modifying enzyme that installed DHU in the RNA molecule. DUS3L crosslinked with …
Hydrogen-bonding interaction of 5,6-dihydrouracil with RNA …
2009年12月15日 · 5,6-Dihydrouracil (DHU) is a rare pyrimidine base naturally occurring in tRNAs, it differs from the base uracil due to the saturation of the C 5 –C 6 bond. This work presents …
Escherichia coli RNA and DNA polymerase bypass of ... - PubMed
1998年4月1日 · Dihydrouracil (DHU) is a DNA base damage product produced in significant amounts by ionizing radiation damage to cytosine under anoxic conditions. DHU represents a …
Transfer RNA - Biology Reader
Transfer RNA is an RNA type that acts as the intermediary element, and plays a significant role in the loading and transferring amino acids to the site of protein synthesis, i.e. Ribosome. The t …
DHU-Pred: accurate prediction of dihydrouridine sites using …
Dihydrouridine (D) is a modified transfer RNA post-transcriptional modification (PTM) that occurs abundantly in bacteria, eukaryotes, and archaea. The D modification assists in the stability and …
带有反密码子的tRNA如何与氨基酸特异性结合？ - 知乎
2023年5月11日 · tRNA的结构可以用“四臂”记忆——受体臂（3’端总是腺嘌呤，氨基酸结合在这个腺嘌呤核苷酸的3’羟基上）、D臂（总是含有二氢尿嘧啶Dihydrouracil，因此得名，图中橙色 …
陆昌瑞 - dhu.edu.cn
2022年7月1日 · 从事 RNA 的结构与功能、基因的表达与调控等研究：核糖核酸开关和其他非编码 RNA 的结构、机理和功能； Packaging RNA (pRNA) 的晶体结构与复合体的包装机理； 外切体 …
Fluorescent labeling of tRNA dihydrouridine residues: Mechanism …
Dihydrouridine (DHU) positions within tRNAs have long been used as sites to covalently attach fluorophores, by virtue of their unique chemical reactivity toward reduction by NaBH 4, their …
转运核糖核酸（tRNA）的结构与功能 - 知乎 - 知乎专栏
转运核糖核酸（transfer ribonucleic acid，tRNA）是一种比较小的RNA，一般由74-93个核苷酸构成，分子量约25 kd，沉降系数4 s。在发现microRNA之前，它是最小的RNA。 tRNA的功能是 …
RNA polymerase bypass at sites of dihydrouracil: implications for ...
Dihydrouracil (DHU) is a major base damage product formed from cytosine following exposure of DNA to ionizing radiation under anoxic conditions. To gain insight into the DNA lesion …
Fluorescent labeling of tRNA dihydrouridine residues: Mechanism …
Dihydrouridine (DHU) positions within tRNAs have long been used as sites to covalently attach fluorophores, by virtue of their unique chemical reactivity toward reduction by NaBH 4, their …