The TMPRSS2/ERG Deletion/Breakapart probe is a three colour probe that consists of green probes and red probes positioned on each side of the TMPRSS2 gene, as well as three blue probes that cover the centromeric region of the ERG gene, up to D21S1439 marker.

2021年3月3日 · LPS-TLR4 engagement has been reported to contribute to MyD88/TRIF-dependent signaling to induce mitochondrial deoxyribonucleotide kinase CMPK2 and dNTP hydrolase SAMHD1 expression in bone...

2021年7月17日 · Padberg and colleagues showed that injection of LPS at 4 ng/kg induces the turnover of kynurenine by activation of IDO1, as measured by the ratio kynurenine/tryptophan, 6–8 h post LPS injection . In the present study, using only half of the LPS dose, we show that the turnover of kynurenine is enhanced up to 48 h post LPS injection.

2021年5月17日 · Here, we investigated the responses of mouse primary microglia upon LPS and poly (I:C) stimulation by detecting various phenotypes ranging from morphology, proliferation, secretion, chemotaxis,...

在本研究中，脂多糖 (lps) 刺激的 bv2 小胶质细胞用于评估 gaa 的抗炎能力。我们的数据表明，gaa 在体外显着抑制 lps 诱导的 bv2 小胶质细胞增殖和激活。更引人注目的是，gaa 促进 bv2 小胶质细胞从 lps 诱导的 m1 状态转变为 m2 状态。

2021年8月19日 · We induced systemic inflammation in mice using the endotoxin lipopolysaccharide (LPS) and used a multimodal approach consisting of in vitro and in vivo bulk RNA-sequencing (RNA-seq), single-cell...

结果表明，铁死亡介导了 LPS 处理的 BEAS-2B 细胞的炎症，而 PX 可能通过抑制铁死亡来改善 LPS 诱导的炎症。同时，PX 可以上调 Keap1-Nrf2/HO-1 通路，并且选择性抑制 Keap1-Nrf2/HO-1 通路显着消除了 PX 在 LPS 处理的细胞中的抗铁死亡和抗炎功能。

This study aimed to investigate whether PD-L1 regulates the inflammation in LPS-induced lung epithelial cells and vascular endothelial cells by interacting with the HIF-1α signaling pathway. Sepsis-induced lung injury mice we …

Lipopolysaccharides（脂多糖），简称为LPS ，革兰氏阴性菌（G-）细胞壁中的一种特有成分，位于细胞壁的最外层并暴露于非荚膜细菌的细胞表面，有利于维持细胞外膜的完整性，保护细菌免受胆汁盐和脂类抗生素的损害。LPS由类脂A、核心多糖和O-多糖侧链组成。

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