Semiautomated Radiosynthesis and Biological Evaluation of [18F]FEAU…
2′-Deoxy-2′- [18 F]fluoro-5-ethyl-1-β- d -arabinofuranosyluracil ( [18 F]FEAU) is a promising radiolabeled nucleoside designed to monitor Herpes Simplex Virus Type 1 thymidine kinase …
Positron emission tomography (PET) imaging with 18 F-based …
Radiochemical purity was >99%, and specific activity was >1800 mCi/μmol at EOS. Synthesis time was 95-100 min from EOB. This direct fluorination is a novel method for the synthesis of …
Semiautomated radiosynthesis and biological evaluation of [18F]FEAU…
2'-deoxy-2'-[(18)F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([(18)F]FEAU) is a promising radiolabeled nucleoside designed to monitor Herpes Simplex Virus Type 1 thymidine kinase …
The improved syntheses of 5-substituted 2′- - ScienceDirect
2011年7月1日 · The efficient automated syntheses of [18 F]FAU, [18 F]FEAU, [18 F]FFAU, [18 F]FCAU, [18 F]FBAU and [18 F]FIAU have been achieved with reasonable yields and high …
Molecular PET imaging of HSV1-tk reporter gene expression
2007年3月8日 · Non-invasive imaging of transgene expression requires the appropriate combination of a reporter gene and a reporter probe. [18 F]FEAU positron emission …
A fully automated synthesis of [18F]‐FEAU and [18F]‐FMAU using …
2009年10月7日 · We report here a fully automated synthesis of [18 F]-FEAU and [18 F]-FMAU on a prototype dual reactor module TRACERlab FX FN. The synthesis was performed by using a …
An improved strategy for the synthesis of [ 18 F]-labeled ...
2012年11月1日 · Using the microwave-driven heating approach, [18 F]-FIAU, [18 F]-FMAU and [18 F]-FEAU have been successfully synthesized within 120 min, affording a radiochemical …
The improved syntheses of 5-substituted 2'-[18F]fluoro-2
The improved radiosyntheses of [(18)F]FAU, [(18)F]FEAU, [(18)F]FFAU, [(18)F]FCAU, [(18)F]FBAU and [(18)F]FIAU have been achieved with reasonable yields and high purity …
Fully automated production of diverse 18F-labeled PET tracers on …
This study demonstrated the versatile use of the ELIXYS fully automated radiosynthesizer to adapt and produce 8 different (18)F-labeled PET tracers of varying complexity.
QC analysis of [18F]FEAU: product injected with standard FEAU ...
Non-invasive imaging of transgene expression requires the appropriate combination of a reporter gene and a reporter probe. [18F]FEAU positron emission tomography (PET) is used for the …