2021年4月29日 · Gain of chromosome 1q (+1q) is one of the most common recurrent cytogenetic abnormalities in multiple myeloma (MM), occurring in approximately 40% of newly diagnosed...

1q21.1 microdeletion is a chromosomal change in which a small piece of chromosome 1 is deleted in each cell. The deletion occurs on the long (q) arm of the chromosome in a region …

2011年2月24日 · The 1q21.1 recurrent deletion itself does not lead to a clinically recognizable syndrome, as some persons with the deletion have no obvious clinical findings.

骨髓瘤主要遗传学异常包括染色体1q21的扩增、13q14缺失，免疫球蛋白重链(IGH)基因重排和17p13(p53)缺失等 ，1号染色体的异常在骨髓瘤中常见，主要有1q获得及1p缺失，虽然1q21 …

Amplification of chromosome 1q (1q21 amp) is one of the most common secondary cytogenetic abnormalities in patients with MM. 1q21 amp is often associated with poor prognosis, drug …

1q21.1 microduplication is a chromosomal change in which a small amount of genetic material on chromosome 1 is abnormally copied (duplicated). The duplication occurs on the long (q) arm …

1q21扩增（以下简称1q）是多发性骨髓瘤（multiple myeloma，MM）中常见的一种细胞遗传学异常，2016年国际骨髓瘤工作组（IMWG）将1q定义为高危遗传学异常之一 [1]。 然而，1q …

Looking at chromosome 1q Chromosomes can’t be seen with the naked eye, but if they are stained and magnified under a microscope, each one has a distinctive pattern of light and dark …

Gain of chromosome 1q (+1q) is one of the most common recurrent cytogenetic abnormalities in multiple myeloma (MM), occurring in approximately 40% of newly...

2024年10月5日 · Chromosome 1q copy number variations, collectively termed +1q, are 1 of the most common cytogenetic abnormalities in multiple myeloma. 1q abnormalities are associated …