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The orphan nuclear receptor HR3 is essential for developmental switches during insect development and metamorphosis regulated by 20-hydroxyecdysone (20E).
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A Critical Role of the Nuclear Receptor HR3 in Regulation of ... - PLOS
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Expression of the early-late gene encoding the nuclear receptor HR3 ...
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The orphan nuclear receptor HR3 is essential for developmental switches during insect development and metamorphosis regulated by 20-hydroxyecdysone (20E).
A Critical Role of the Nuclear Receptor H…
journals.plos.org/plosone/article?id=10.1371/journa…
The insect steroid hormone, 20-hydroxyecdysone (20E), is a key factor controlling critical developmental events of embryogenesis, larval molting, metamorphosis, and, in some insects, reproduction.
Expression of the early-late gene encodin…
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ScienceDirect
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Nuclear receptor HR3 controls locust molt by regulating chitin ...
2018年1月1日 · During growth and development of insects, the steroid hormone 20-Hydroxyecdysone (20E) regulates the molting process through activation of a series of genes …
作者: Xiaoming Zhao, Zhongyu Qin, Weimin Liu, Xiaojian Liu, Bernard Moussian, Enbo Ma, Sheng Li, Jianzhen ...
Publish Year: 2018
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X-MOL科学知识平台
https://www.x-mol.com › paper
基于转录组的分析揭示了 20E/HR3 通路在菜青虫滞育中的关键作 …
2024年1月11日 · 当将20e注射到滞育蛹中时，表达水平提高，并且蛹滞育被打破。这些结果表明20E/HR3途径是滞育调节的关键途径，通过蜕皮激素处理或RNAi干扰该途径将导致滞育的破坏。
ScienceDirect
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Transcriptome-based analysis reveals a crucial role of the 20E/HR3 ...
2024年2月1日 · In our study, we demonstrated that 20E/HR3 is a crucial pathway in regulating diapause in P. rapae, and perturbing this pathway by ecdysone treatment or RNAi would result …
ScienceDirect
https://www.sciencedirect.com › science › article › pii
20-Hydroxyecdysone (20E) Primary Response Gene E75
2016年8月26日 · HR3 controls the termination of the 20E signal pulse, which triggers the larval-prepupal transition by both inhibiting 20E-EcR-USP transactivation by interacting with EcR and …
- 作者: Kang Li, Ling Tian, Zhongjian Guo, Sanyou Guo, Jianzhen Zhang, Shi-Hong Gu, Subba Reddy Palli, Yang ...
- Publish Year: 2016
MDPI
https://www.mdpi.com
RNAi Suppression of Hormone Receptor HR3 Blocks Larval …
2022年7月19日 · Hormone receptor 3 (HR3), an early-late gene of the 20-hydroxyecdysone (20E) signaling pathway, plays a critical role in insect metamorphosis and development. In this …
万方数据知识服务平台
https://d.wanfangdata.com.cn › thesis
LncRNA靶HR3调控赤拟谷盗蜕皮和变态的机制-学位-万方数据知识 …
本研究发现hr3与hr3l在赤拟谷盗中调控蜕皮和变态的功能以及hr3l通过部分反向互补靶向hr3调控其表达，揭示hr3和hr3l可能通过foxo偶联20e通路调控赤拟谷盗的蜕皮和变态，利用rna-seq初步 …
其他用户还问了以下问题
Is hr3 activated by 20E and betaftz-f1?
In vitro FB culture experiments have shown that HR3 is activated by 20E, while betaFtz- F1 is inhibited; this is in agreement with observed in vivo expression patterns of these nuclear receptors , .
A Critical Role of the Nuclear Receptor HR3 in Regulation of ... - PLOS
journals.plos.org
How does hr3 regulate ecdysone synthesis?
HR3 controls the termination of the 20E signal pulse, which triggers the larval-prepupal transition by both inhibiting 20E-EcR-USP transactivation by interacting with EcR and blocking ecdysone biosynthesis by down-regulating the Halloween family of cytochrome P450 genes (Halloween genes).
20-Hydroxyecdysone (20E) Primary Response Gene E75 ... - ScienceDirect
sciencedirect.com
How does hr3 RNAi depletion affect the 20E response?
The effect of HR3 RNAi depletion on transcript levels of genes involved in the 20E response in the fat body of Aedes female mosquitoes during the first and the second gonadotrophic cycles. Transcript abundance of EcRA, EcRB, USPA, USPB, betaFTZ-F1A, and betaFTZ-F1B is represented.
A Critical Role of the Nuclear Receptor HR3 in Regulation of ... - PLOS
journals.plos.org
Is 20e a cyclic hormone?
Reproduction of female mosquitoes of the major vector of Dengue fever, Aedes aegypti, is cyclic because of its dependence on blood feeding. 20E is an important hormone regulating vitellogenic events in this mosquito; however, any role for HR3 in 20E-driven reproductive events has not been known.
A Critical Role of the Nuclear Receptor HR3 in Regulation of ... - PLOS
journals.plos.org
Is hr3 a key regulator of 20e-mediated reprogramming in insect metamorphosis?
The orphan nuclear receptor HR3, a key regulator of 20E-mediated reprogramming in insect metamorphosis – , , , is also expressed in the adult female mosquito A. aegypti. In the female mosquito, its transcript is highly elevated during the larval-pupal transition and during the peak of vitellogenesis , , .
A Critical Role of the Nuclear Receptor HR3 in Regulation of ... - PLOS
journals.plos.org
What is the role of the orphan nuclear receptor hr3?
The orphan nuclear receptor HR3 is recognized as a central regulator in 20E-driven developmental switches during insect development and metamorphosis, and is responsible for directing timely shutdown of early genes regulated by a preceding 20E peak and a sequential activation of factors by a subsequent pulse of 20E ( Fig. S1) – .
A Critical Role of the Nuclear Receptor HR3 in Regulation of ... - PLOS
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PubMed
https://pubmed.ncbi.nlm.nih.gov
Expression of the early-late gene encoding the nuclear receptor …
2000年2月25日 · The insect steroid hormone, 20-hydroxyecdysone (20E), is a key factor controlling critical developmental events of embryogenesis, larval molting, metamorphosis, …
plos.org
https://journals.plos.org › plosone › article
A Critical Role of the Nuclear Receptor HR3 in …
2012年9月26日 · The orphan nuclear receptor HR3 is recognized as a central regulator in 20E-driven developmental switches during insect development and metamorphosis, and is responsible for directing timely shutdown of early …
gzu.edu.cn
https://entomol.gzu.edu.cn › page.htm
贵州大学昆虫所李海银副教授团队：基于转录组，揭示2…
2024年1月15日 · 在本研究中，李海银副教授团队基于转录组测序，综合运用qpcr、激素注射、rnai等技术手段，揭示了20e/hr3通路在菜青虫滞育调节中的关键作用。【研究内容】
PubMed
https://pubmed.ncbi.nlm.nih.gov
Transcriptome-based analysis reveals a crucial role of the 20E/HR3 ...
When 20E was injected into diapause pupae, the HR3 expression levels were improved, and the pupal diapause were broken. These results indicate that the 20E/HR3 pathway is a critical …
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