2019年10月1日 · This review summarizes both 3' UTR functions-the regulation of mRNA and protein-based processes-and highlights how each 3' UTR function was discovered with a …

3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are best known to regulate mRNA-based processes, such as mRNA localization, mRNA stability, and translation. In …

Here we review available information about human 3′ UTRs, known classes of 3′ UTR cis elements, evidence that supports the importance of 3′ UTRs in lung disease, and recent …

2017年11月27日 · 3'-untranslated regions (3'-UTRs) are the noncoding parts of mRNAs. Compared to yeast, in humans, median 3'-UTR length has expanded approximately tenfold …

2024年2月1日 · We propose that 3′ UTR variants that disrupt (or create) specific types of regulatory elements are more likely to alter function and contribute to disease, aiding in the …

In this review, we discuss the diverse modes of translational regulation by 3′-UTR-binding proteins and the experimental and conceptual advances provided by current high-throughput …

2012年5月1日 · In this review, we summarize the information known to date about 3'end processing, sequence characteristics including related binding proteins and the role of 3'UTRs …

2003年8月1日 · Adding to the complexity, 3′ untranslated regions (UTRs) often contain several regulatory elements that govern the spatial and temporal expression of an mRNA. …

2020年5月12日 · Surprising roles for 3' UTRs are emerging beyond the regulation of protein synthesis and include roles as RBP delivery scaffolds and regulators of alternative splicing. …

3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are best known to regulate mRNA-based processes, such as mRNA localization, mRNA stability, and translation. In ad …