
What Are 3' UTRs Doing? - PubMed
2019年10月1日 · This review summarizes both 3' UTR functions-the regulation of mRNA and protein-based processes-and highlights how each 3' UTR function was discovered with a …
What Are 3′ UTRs Doing? - PMC - PubMed Central (PMC)
3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are best known to regulate mRNA-based processes, such as mRNA localization, mRNA stability, and translation. In …
Toward a Systematic Understanding of mRNA 3′ Untranslated …
Here we review available information about human 3′ UTRs, known classes of 3′ UTR cis elements, evidence that supports the importance of 3′ UTRs in lung disease, and recent …
Regulation by 3'-Untranslated Regions - PubMed
2017年11月27日 · 3'-untranslated regions (3'-UTRs) are the noncoding parts of mRNAs. Compared to yeast, in humans, median 3'-UTR length has expanded approximately tenfold …
Regulatory features aid interpretation of 3′UTR variants
2024年2月1日 · We propose that 3′ UTR variants that disrupt (or create) specific types of regulatory elements are more likely to alter function and contribute to disease, aiding in the …
Translational control by 3′-UTR-binding proteins - PMC
In this review, we discuss the diverse modes of translational regulation by 3′-UTR-binding proteins and the experimental and conceptual advances provided by current high-throughput …
Full article: The role of the 3' untranslated region in post ...
2012年5月1日 · In this review, we summarize the information known to date about 3'end processing, sequence characteristics including related binding proteins and the role of 3'UTRs …
The power of the 3′ UTR: translational control and development
2003年8月1日 · Adding to the complexity, 3′ untranslated regions (UTRs) often contain several regulatory elements that govern the spatial and temporal expression of an mRNA. …
Emerging Roles for 3' UTRs in Neurons - PubMed
2020年5月12日 · Surprising roles for 3' UTRs are emerging beyond the regulation of protein synthesis and include roles as RBP delivery scaffolds and regulators of alternative splicing. …
3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are best known to regulate mRNA-based processes, such as mRNA localization, mRNA stability, and translation. In ad …
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