Jun 10, 2008 · Crystal structures of caspase-3 in complexes with isoquinoline-1,3,4-trione derivatives show that the catalytic cysteine is oxidized to sulfonic acid (-SO (3)H) and …

Crystal Structures of Caspase-3 with Bound Isoquinoline-1,3,4-trione Derivative Inhibitors

Oct 31, 2008 · We report here the mechanism of caspase-3 inactivation by isoquinoline-1,3,4-trione derivatives. Kinetic analysis indicates the compounds can irreversibly inactivate caspase …

3DEH: Crystal Structures Of Caspase-3 With Bound Isoquinoline-1,3,4-trione Derivative Inhibitors. PDB ID: 3DEH Download: MMDB ID: 66478: PDB Deposition Date: 2008/6/10: Updated in …

Sep 2, 2008 · 3deh: Isoquinoline-1,3,4-trione derivatives inactivate caspase-3 by generation of reactive oxygen species.

3DEH: Crystal Structures of Caspase-3 with Bound Isoquinoline-1,3,4-trione Derivative Inhibitors

PDB Entry: 3deh (more details), 2.5 Å PDB Description : crystal structures of caspase-3 with bound isoquinoline-1,3,4-trione derivative inhibitors PDB Compounds : (A:) Caspase-3

3deh is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. …

As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users …

(a) STM topography of the Cu-coordinated 3deh-DPDI network after measuring interaction curves above Ar, Kr and Xe atoms. (b) Frequency shift curves taken at the equivalent node sites with …