中山大学 | 纳米脂质体可通过焦亡和cGAS-STING活化增强TNBC治 …
PEG-cRGD表面修饰不仅提高了其稳定性，而且增强了其靶向肿瘤的能力。在内源性高水平H2O2存在的4T1细胞中，被包裹的MnCO分解为Mn2+和CO，导致caspase-3激活。活化 …
ROS induction within 4T1 breast cancer cells by CuS NPs as …
2023年9月1日 · Results not only confirmed ROS generation ability of CuS@Alg NPs within cells, but also show the anticancer ability of them. By CDT, the created smart nanoscale system …
The role of reactive oxygen species in the immunity induced …
2021年12月9日 · We found that NPS treatment enhanced the immunogenicity of 4T1-luc mouse mammary tumor, resulted in a potent in situ vaccination protection and induced long-term T …
Mitochondria-specific drug release and reactive oxygen species …
2019年4月12日 · To this aim, 4T1 tumor-bearing mice were intravenously injected with different formulations for 8 h followed by the intraperitoneal administration of the ROS probe, Cellular …
Biomaterials：ROS诱导的放疗增敏与纳米光疗联合治疗根治原位乳 …
在纳米光疗中以低剂量（6 gy），ros引起的增敏rt的原位4t1乳腺癌小鼠中观察到完全根除原发肿瘤和强效抑制肺转移，83％小鼠的生存率可达到60天。 原文链接：
Triple synergistic enhancement of breast cancer treatment via ...
2025年3月21日 · The fluorescent probe DCFH-DA was used to determine the level of ROS production in cells after material treatment. 4T1 cells were inoculated into 24-well plates at a …
A Robust ROS Generation and Ferroptotic Lipid Modulation …
2024年10月1日 · Based on these two strategies for ROS generation, we have developed a robust ROS generation nanosystem loaded with AA (denoted as CTFAP) for mutually reinforcing …
Hybrid nanoparticle–mediated simultaneous ROS scavenging
2024年9月18日 · We designed a hybrid nanoparticle–based ISV, which accomplished superior cancer immunotherapy via simultaneously scavenging reactive oxygen species (ROS) and …
沈折玉课题组在《ACS Nano》发表学术成果: 肿瘤原位产生的活性 …
2023年6月15日 · 体外和体内实验结果均验证了该策略能在肿瘤细胞内特异性产生ROS风暴，并实现了小鼠乳腺癌的高效铁死亡治疗。该研究成果以“Tumor-Generated Reactive Oxygen …
A tumor-specific ROS self-supply enhanced cascade-responsive …
2023年7月1日 · To explore the cascade self-amplifying prodrug activation of PPHI@B/L, the intracellular ROS generation was examined in 4T1 cells. Dichlorofluorescein diacetate (DCF …