2018年3月1日 · After 60 min, iTLC results from the crude reaction showed better radiolabeling with the 89 Zr- (LT) (55%) than 89 Zr- (ST) (33%). FollowingPD-10 purification and …

In the present study, we determined that a lower concentration of H2C2O4 eluent (0.8M) is adequate to efficiently remove (89)Zr from a column containing 100mg hydroxamate resin. As …

2020年11月1日 · Our results demonstrate that [89 Zr]Zr-oxine is a suitable PET alternative to [111 In]In-oxine for WBC imaging. Our formulation allows rapid, stable, high-yield, single-step …

2022年1月13日 · Clinical production of 89 Zr-radiolabeled antibodies (89 Zr-mAbs) for positron emission tomography imaging relies on the pre-conjugation of desferrioxamine B (DFO) to the …

使用 iTLC 和尺寸排阻色谱评估放射性偶联物的完整性。 这项研究表明，螯合剂和生物分子之间接头的性质会对 89个 Zr 标记偶联物的稳定性以及偶联物的聚集产生重大影响。

2024年1月5日 · Here, we report the synthesis and evaluation of a zirconium-89 labelled C1–3 radioimmunoconjugate, and demonstrate that [89 Zr]Zr-DFO-C1–3 successfully differentiates …

2021年7月6日 · Our study demonstrates that [89 Zr]Zr-oxine and [89 Zr]Zr-DFO-NCS are equally effective in cell labelling. However, [89 Zr]Zr-oxine was superior to [89 Zr]Zr-DFO-NCS with …

2024年9月1日 · In this work, we report on a suitable application of TK400 Resin to remove iron during [89 Zr]ZrCl 4 radiochemical isolation. The breakthrough allows for direct radiolabeling of …

2020年10月7日 · Under these ITLC conditions, ‘free’ 89 Zr 4+ ions are rapidly coordinated by DTPA to give the [89 Zr] [Zr (DTPA)] – complex, which migrates to the solvent front (Rf = 1.0).

89 Zr (t1/2 = 78.4 h), a positron-emitting metal, has been exploited for PET studies of antibodies because of its relatively long decay time and facile labeling procedures. Here, we used 89 Zr …