Background and purpose: Lipoxin A4 (LXA4) has been reported to reduce inflammation in several neurological injury models. We studied the effects of LXA4 on neuroinflammation after …

The aim of this study was to investigate the protective effects and underlying anti-oxidative molecular mechanism of lipoxin A4 (LA4) in rats with ischemia/reperfusion (I/R)-injured …

A rat model of monosodium iodoacetate (MIA)-induced KOA was constructed and intervened with moderate-intensity treadmill exercise and intraperitoneal injection of PHTPP to investigate the …

This study aims to investigate the pre- and postconditioning effects of lipoxin A4 (LXA4) on myocardial damage caused by ischemia/reperfusion (I/R) injury. Seventy-two rats were divided …

2021年7月14日 · In this study, we found that lipoxin A4 significantly ameliorated the lung injury after lung transplantation in rats. Lipoxin A4 not only reduced the ischaemia reperfusion …

2025年1月1日 · LXA4 decreased cerebral infarction and brain water content, improved neurological deficits, and reduced the release of NETs-associated indicators (MPO, NE) in …

2025年2月15日 · Since this study represents the first attempt to evaluate the therapeutic potential of aspirin-triggered lipoxin A4 (ATL) and its combination with cannabinoid receptor agonists in …

Our results showed that LXA4 treatment significantly promotes skin flap survival and attenuates I/R injury by inhibiting oxidative stress, apoptosis, and inflammatory factor release, evidenced …

2020年11月22日 · Lipoxin A4 is an endogenous anti-inflammatory and antioxidant mediator. The present study determined the effects of lipoxin A4 on VILI. Twenty-four rats were randomized …

近日，来自中国医科大学附属盛京医院骨科的研究者们在Redox Biol杂志上发表了题为“Lipoxin A4 ameliorates knee osteoarthritis progression in rats by antagonizing ferroptosis through …