A549 cells were isolated from the lung tissue of a White, 58-year-old male with lung cancer. This cell line can be used in cancer, immuno-oncology, and toxicology research.

The A549 cell lines are the most commonly used human non-small cell lung cancer cell lines for both basic research and drug discovery. In this article, we will cover every topic about this cell line, ranging from general information to research applications.

STR analysis according to the global standard ANSI/ATCC ASN-0002.1-2021 (2021) resulted in an authentic STR profile of the reference STR database.

The A549 cell line, emblematic of human non-small cell lung cancer, originates from the adenocarcinoma subtype within the alveolar epithelial cells. These cells offer a versatile model for a wide array of investigations in cancer biology, toxicology, and immuno-oncology.

Characteristics: Expresses HPRT1 at the surface of the cell membrane (PubMed= 28408844). Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed= 29468137).

We examined A549 cell growth in different media over long term culture and then used microarray analysis to investigate temporal regulation of pathways involved in cell cycle and ATII differentiation; we also made comparisons with gene expression in …

The A549 cell line is a widely used human lung adenocarcinoma cell line that was derived from a primary lung tumor. A549 cells are highly proliferative and have been used in a wide variety of research applications.

A549 is a human epithelial cell line derived from a lung carcinoma tissue. The cells are adherent in culture. The karyotype is hypotriploid male with a modal chromosome number of 12. There are numerous chromosome abnormalities and marker chromosomes.

2023年6月19日 · A549 is a human lung adenocarcinoma cell line that was derived from a male patient in 1972. It is commonly used as a model for studying lung cancer and respiratory diseases. A549 cells have several characteristics that …

2016年5月1日 · Today a large number of human non-small cell lung cancer cell lines exist that are being used for both basic research and drug discovery. One commonly used line is A549, an epithelial carcinoma derived from a 58 year old male patient, known to be KRAS mutant and EGFR wild type.