Among AAbs, those recognizing β1AR-AAbs show agonist-like effects, have detrimental effects on cardiomyocytes, and may induce persistent myocardial damage. Methods: We quantify total IgG and IgG3 subclass β1AR-AAb in subjects with chronic stable HF with long-term follow-up.

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Β 1 AR-Aabs have agonist effects inducing desensitization of β 1 AR, cardiomyocyte apoptosis, and sustained calcium influx which lead to cardiac dysfunction and arrhythmias. Β 1 AR-Aab has been reported to be detected in approximately 40% of patients with DCM, and the presence of the antibody has been associated with worse clinical outcomes.

2022年7月13日 · 本文详细解读Google Play新政策要求的应用包格式转换，介绍了aab的优势、安装过程、打包流程，以及如何利用bundletool进行转换和操作。

2024年12月18日 · Android App Bundles（AAB）是一种新的应用发布格式，它是Google为了解决APK格式存在的问题而推出的一种解决方案。 与传统的APK文件不同，AAB不是一个包含应用所有资源的单一文件，而是一个包含所有代码、资源和配置的容器。 这个容器通过Google Play的**动态交付（Dynamic Delivery）**技术，可以根据用户设备的特性（如屏幕密度、CPU架构、语言设置等）生成最适合该设备的APK，从而提供更小、更高效的应用包。 换句话说，AAB让开发 …

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2021年6月5日 · 简单地说aab就是一个带有很多分包数据的压缩包。 它将一个apk拆分了多个小包，比如按CPU架构拆分，按语言拆分等等，最终移动设备安装时只需要下载需要的分包即可。

2021年7月8日 · 谷歌表示，自 AAB 发布以来，开发者社区积极拥护这一全新发布格式，并受益于其简化的发布管理和高级分发功能。 目前，有超过一百万款正式版应用使用 AAB 格式，Google Play 上排名前 1,000 的大多数应用和游戏均在此列，例如 Adobe、Duolingo …

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3 天之前 · Learn more about the American Heart Association's efforts to reduce death caused by heart disease and stroke. Also learn about cardiovascular conditions, ECC and CPR, donating, heart disease information for healthcare professionals, caregivers, and …