A Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM10 or CDw156 or CD156c is a protein that in humans is encoded by the ADAM10 gene. [5] …

2024年12月24日 · ADAM10 (ADAM Metallopeptidase Domain 10) is a Protein Coding gene. Diseases associated with ADAM10 include Reticulate Acropigmentation Of Kitamura and …

2025年2月8日 · ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion. ADAM10-cleaved ephrin-A5 contributes to prostate cancer …

Human ADAM10 is localized on chromosome 15 (15q22) and is widely expressed in mammalian organs, including brain. The role of ADAM10 as α-secretase cleaving APP has been confirmed …

2025年1月23日 · A Disintegrin and Metalloprotease 10, also known as ADAM10, is a cell surface protease ubiquitously expressed in mammalian cells where it cuts several membrane proteins …

As a member of the A Disintegrin And Metalloproteinase (ADAM) family, ADAM10 has been identified as the constitutive α-secretase in the process of amyloid-β protein precursor (AβPP) …

We will discuss some examples of ADAM10 activity modulated by changing partners and subcellular compartmentalization, with the underlying hypothesis that restraining protease …

2018年9月21日 · This study shows that ADAM10 is the receptor for the staphylococcal toxin α-haemolysin in vivo and identifies ADAM10 activity as a novel therapeutic target for α …

The ubiquitously expressed transmembrane protein a disintegrin and metalloproteinase 10 (ADAM10) functions as a “molecular scissor”, by cleaving the extracellular regions from its …

2020年3月24日 · Generating inhibitors for A Disintegrin And Metalloproteinase 10 (ADAM10), a zinc-dependent protease, was heavily invested in by the pharmaceutical industry starting over …