2024年12月24日 · AIMP2 (Aminoacyl TRNA Synthetase Complex Interacting Multifunctional Protein 2) is a Protein Coding gene. Diseases associated with AIMP2 include Leukodystrophy, Hypomyelinating, 17 and Inherited Cancer-Predisposing Syndrome. Among its related pathways are Peptide chain elongation and NRF2-ARE regulation.

AIMP2 - aminoacyl tRNA synthetase complex interacting multifunctional protein 2 Gene

2020年7月24日 · In this review, we summarize the biological functions of AIMP1, EMAP II, AIMP2, AIMP2-DX2, and AIMP3. Also, we systematically introduce their emerging roles in cancer, aiming to provide new...

AIMP : Free Audio Player : Официальный сайт программы. What's new? General: localizations has been updated; General: the %Total macro has been added

2022年5月11日 · Here, we report that AIMP2-DX2, a variant of the tumor suppressor AIMP2 (aminoacyl-tRNA synthetase-interacting multi-functional protein 2), acts as a cancer-specific regulator of KRAS stability...

AIMP2-DX2 is a variant of AIMP2 produced by alternative splicing, resulting in the deletion of exon 2. It has been found in a variety of cancer cell lines and tissues. Through competitive interactions with p53, FBP, and TRAF2, this variant can still inhibit the tumor-suppressive function of native AIMP2, even though it is no longer able to ...

Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex. AIMP2-DX2 plays an important role in the regulation of Nasopharyngeal carcinoma. Homozygosity for a nonsense variant in AIMP2 is associated with a progressive neurodevelopmental disorder with microcephaly, seizures, and spastic quadriparesis.

2020年11月11日 · Here, we found that AIMP2 exhibits a self-aggregating property. The AIMP2 aggregate serves as a seed to increase α-synuclein aggregation via specific and direct binding to the α-synuclein monomer. The coexpression of AIMP2 and α-synuclein in cell cultures and in vivo resulted in the rapid formation of α-synuclein aggregates with a ...

2024年5月5日 · AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [ Homo sapiens (human) ] Gene ID: 7965, updated on 5-May-2024 Download Datasets

AIMP : Free Audio Player : Официальный сайт программы. Download: Download (15.2 MB) 32-bit File Size: 15.2 MB SHA256 ...