AKR1C1 Gene - GeneCards | AK1C1 Protein | AK1C1 Antibody
2024年12月24日 · AKR1C1 (Aldo-Keto Reductase Family 1 Member C1) is a Protein Coding gene. Diseases associated with AKR1C1 include Developmental Dysplasia Of The Hip 1 and …
AKR1C1 - Wikipedia
This specific enzyme, AKR1C1, among other reactions, catalyzes the reduction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. The AKR1C1 gene shares high sequence …
The AKR1C1–CYP1B1–cAMP signaling axis controls ... - Nature
2024年10月30日 · Based on genomic analysis of ECC patient samples, here we report that aldo-keto reductase family 1 member C1 (AKR1C1) is highly expressed in human ECC tissues and …
Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, …
Aldo–keto reductases comprise of AKR1C1–AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and …
AKR1C1 interacts with STAT3 to increase intracellular ... - PubMed
In the present study, we demonstrate that the aldo-keto reductase 1C1 (AKR1C1) is overexpressed in CRC cells upon acquisition of OXA resistance, evident in OXA-resistant …
AKR1C1 aldo-keto reductase family 1 member C1 [ (human)]
AKR1C1 is a crucial regulator for cisplatin-resistance in HNSCC and also poor prognostic marker for patients. Targeting the AKR1C1-STAT axis may provide a new therapeutic strategy to treat …
铁死亡相关基因 AKR1C1 作为与免疫微环境和乳腺癌预后相关的新 …
结果：两个铁死亡相关基因（AKR1C1和AKR1C3 ) 在 GSE22358、GSE9014 和 GSE8977 中显着表达。 AKR1C1的高表达与良好的预后相关。 TCGA- BRCA进一步证实了AKR1C1的表达 …
醛酮还原酶家族 1 成员 C1（AKR1C1）基因 | MCE
该基因编码醛/酮还原酶超家族的一个成员，该家族由 40 多种已知的酶和蛋白质组成。 这些酶利用 NADH 和/或 NADPH 作为辅助因子，催化醛和酮转化为其相应的醇。 这些酶显示重叠但不同的 …
AKR1C1在恶性肿瘤中的研究进展 - 百度学术
人20α-羟基类固醇脱氢酶 (aldo-keto reductase family 1member C1,AKR1C1)是醛酮还原酶 (aldo-keto reductase,AKRs)超家族成员之一.AKR1C1的功能: (1)调节雄激素,雌激素和孕激素的代谢, …
AKR1C1 connects autophagy and oxidative stress by interacting with ...
2021年5月20日 · Aldo-keto reductase family 1 member C1 (AKR1C1) mainly catalyses the reduction of progesterone by utilising NADP + (oxidised form of nicotinamide adenine …