2021年8月10日 · Frontotemporal degeneration or frontotemporal dementia (FTD) refers to a group of disorders that causes progressive damage to the temporal and frontal lobes of the …

2025年3月14日 · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration is the official journal of the World Federation of Neurology Research Group on Motor Neuron Diseases. It …

In 2011, researchers identified a variant in the C9orf72 gene as the most common cause of both genetic FTD and genetic amyotrophic lateral sclerosis (ALS). Previously, ALS was thought to …

This article presents the revised consensus criteria for the diagnosis of frontotemporal dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research workshop on …

2013年8月7日 · Breakthrough discoveries identifying common genetic causes for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) have transformed our view of these …

In contrast with ALS-ci/bi cases, when patients with ALS had co-occurrent dementia (ALS-FTD), our study has outlined not only a pattern of microstructural damage involving motor networks …

There is increasing recognition of a clinical overlap between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Recent advances in our understanding of the …

2025年3月20日 · The ALS-FTD disease spectrum. Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are both fatal and progressive adult-onset neurodegenerative …

4 天之前 · Background Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share overlapping clinical, genetic, and neuroimaging features; a spectrum of conditions …

2018年8月17日 · In this article, we review the pathological and mechanistic features of C9orf72 -associated FTD and ALS (collectively termed C9FTD/ALS), the model systems used to study …