In our opinion, patients who have liver involvement with AML should be offered alternative investigational therapies with a low hepatic toxicity profile. Key Words: Acute myeloid leukemia, Liver, Transaminitis. A 66-year-old woman presented with a two-month history of progressive mid-thoracic back pain with anorexia and 10 pounds weight loss.

2023年2月10日 · Hepatic angiomyolipomas (AML) are uncommon benign hamartomatous hepatic mass lesions, containing blood vessel (angioid), smooth muscle (myoid) and mature fat (lipoid) components. There is an association with tuberous sclerosis, …

Epithelioid angiomyolipoma (AML) of the liver is a rare benign mesenchymal tumor that usually presents in adult female patients; nonetheless, several cases have also been reported among males. AMLs most frequently occur in the kidney, with the liver being the second most common site of involvement (1).

2008年3月14日 · Liver involvement with acute myeloid leukemia (AML) is rarely reported. The majority of published cases suggest a cholestatic picture and obstructive jaundice at presentation. On the contrary, our patient presented with transaminitis without cholestasis. Elevated liver function tests persisted in ou …

In patients presenting with acute liver failure (ALF), acute myeloblastic leukaemia (AML) is extraordinarily rare and is associated with very high mortality. We cared for a patient who presented with acute hepatic failure and was diagnosed with AML on autopsy (albeit suspected immediately pre-mortem).

Although liver infiltration by AML is rare, it should be considered early. It usually presents with elevated LFTs in a mixed hepatocellular and cholestatic pattern. In addition to our case, there are several case reports suggesting AML as an etiology of elevated LFTs.

2024年12月1日 · Peripheral blood smear revealed notable myeloblasts and auer rods. Bone marrow aspiration smear showed over 20% myeloblasts, supporting the diagnosis of acute myeloid leukemia. Flow cytometry analysis was evaluated as consistent with AML. Abdominal ultrasonography revealed the liver was 19.5 cm and the spleen was 16 cm in size.

2021年1月1日 · Extramedullary leukemia infiltration of liver can delay initiation of chemotherapy. Hydroxyurea may be employed as a temporizing measure for effects of hyperleukocytosis. We present the case of a 55-year-old woman who presented with laboratory studies concerning for acute myeloid leukemia (AML) as well as obstructive cholestasis.

2025年1月8日 · Whilst severe liver dysfunction is rarely encountered at the time of diagnosis for patients with acute myeloid leukemia (AML), mild elevations aminotransferase (<5 times the upper limit of normal) may be more frequently seen.

2011年9月1日 · Liver angiomyolipomas (AML) are mesenchymal neoplasms with an uncertain clinical behavior. The spectrum of presentation, imaging and histologic features, and outcomes were analyzed in all patients treated at Memorial Sloan-Kettering Cancer Center.