Apolipoprotein L1 (apoL1) is a minor apolipoprotein component of HDL cholesterol which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. …

2024年12月24日 · APOL1 (Apolipoprotein L1) is a Protein Coding gene. Diseases associated with APOL1 include Focal Segmental Glomerulosclerosis 4 and Glomerulonephritis. Among its …

关于 apol1 Cytogenetic location: 22q12.3 Genomic coordinates (GRCh38): 22:36,253,133-36,267,525 (from NCBI) This gene has 10 transcripts (splice variants), 509 orthologues, 6 …

2022年2月25日 · Genetic coding variants in APOL1, which encodes apolipoprotein L1 (APOL1), were identified in 2010 and are relatively common among individuals of sub-Saharan African …

What is the APOL1 Gene? Apolipoprotein L1 (APOL1) is a gene located on chromosome 22, and has two coding variants, G1 and G2. APOL1 produces a protein that is a component of …

2021年7月27日 · Apolipoprotein L1 (ApoL1) is a circulating innate immunity protein protecting against trypanosome infection. However, two ApoL1 coding variants are associated with a …

2024年2月14日 · Apolipoprotein L1 (APOL1) circulates in the blood and protects humans against infection by African trypanosomes 1. APOL1 variants G1 (S342G, I384M) and G2 …

2024年12月30日 · This review summarizes current understanding about the genetic, molecular, and clinical features of APOL1-associated FSGS and investigates new therapeutic options. It …

APOL1 is a member of the six-member APOL gene cluster located in human chromosome 22 (6 – 8). APOL1 has unique features compared with other APOL family proteins. APOL1 was initially …

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. …