ATF6 Gene - GeneCards | ATF6A Protein | ATF6A Antibody
2024年12月24日 · ATF6 (Activating Transcription Factor 6) is a Protein Coding gene. Diseases associated with ATF6 include Achromatopsia 7 and Achromatopsia. Among its related …
Molecular mechanism of ATF6 in unfolded protein response and …
2024年3月15日 · Activating transcription factor 6 (ATF6), an important signaling molecule in unfolded protein response (UPR), plays a role in the pathogenesis of several diseases, …
A lifetime of stress: ATF6 in development and homeostasis
2018年5月25日 · Best known for its role in transducing signals linked to stress to the endoplasmic reticulum, the 50 kDa activated form of ATF6 is now emerging as a major regulator of …
ATF-6 (D4Z8V) Rabbit mAb | Cell Signaling Technology
Activating Transcription Factor - 6 (ATF-6) is a transmembrane glycoprotein of the endoplasmic reticulum (ER). Upon accumulation of improperly folded proteins in the ER, ATF-6 is cleaved …
ATF6 在未折叠蛋白反应中的分子机制及其在疾病中的作用,Heliyon …
2024年2月10日 · 激活转录因子 6 （ATF6） 是未折叠蛋白反应 （UPR） 中的重要信号分子，在多种疾病的发病机制中发挥作用，包括先天性视网膜疾病、肝纤维化和强直性脊柱炎等疾病。 …
ATF6 - Wikipedia
ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules. [8] Accumulation of misfolded proteins in the …
ATF6 - an overview | ScienceDirect Topics
ATF6 is an ER type-II transmembrane protein with a N-terminal cytoplasmic region containing a bZIP and DNA transcription activation domain and a C-terminal lumenal region that senses ER …
Pancreatic β-cells depend on basal expression of active ... - PubMed
2012年4月1日 · ATF6 functions to increase ER capacity by stimulating transcription of ER-resident chaperone genes such as GRP78. Using an antibody that recognizes active ATF6α …
Entry - *605537 - ACTIVATING TRANSCRIPTION FACTOR 6; ATF6 …
2016年5月9日 · ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules (summary by Shen et al., …
ATF6 as a Nodal Regulator of Proteostasis in the Heart
2020年4月8日 · This cleavage liberates the N-terminal 50 kD cytosolic portion of ATF6, which has a nuclear localization sequence, facilitating its movement to the nucleus, where it acts as a …