Ataxin-2 - Wikipedia
Ataxin-2 is a protein that in humans is encoded by the ATXN2 gene. [5][6] Mutations in ATXN2 cause spinocerebellar ataxia type 2 (SCA2). Ataxin-2 contains the following protein domains: …
ATXN2 Gene - GeneCards | ATX2 Protein | ATX2 Antibody
2024年12月24日 · ATXN2 (Ataxin 2) is a Protein Coding gene. Diseases associated with ATXN2 include Spinocerebellar Ataxia 2 and Parkinson Disease, Late-Onset. Among its related …
老蛋白新功能，相分离领域的又一重大突破
2019年4月12日 · Ataxin-2是人类中由ATXN2基因编码的蛋白质。ATXN2的突变引起2型脊髓小脑性共济失调（SCA2）。Ataxin-2通过其与poly（A）结合蛋白的相互作用参与调节mRNA翻译。 …
The polyglutamine protein ATXN2: from its molecular functions to …
2024年6月14日 · Ataxin-2 (ATXN2) is a versatile protein with key roles in several molecular, cellular, and physiological functions. For example, it binds RNA but also plays a crucial role in …
Ataxin-2 gene: a powerful modulator of neurological disorders
Polymorphisms and intermediate alleles in ATXN2 establish this gene as a powerful modulator of neurological diseases including lethal neurodegenerative conditions such as motor neuron …
Ataxin-2: a powerful RNA-binding protein | Discover Oncology
2024年7月22日 · Ataxin-2 (ATXN2) was originally discovered in the context of spinocerebellar ataxia type 2 (SCA2), but it has become a key player in various neurodegenerative diseases. …
Ataxin-2 gene: a powerful modulator of neurological disorders
2021年8月1日 · ATXN2 is one of the few genes where a single gene causes several diseases and/or modifies several and disparate neurological disorders. Hence, understanding …
ATXN2 ataxin 2 [Homo sapiens (human)] - Gene - NCBI
2025年1月5日 · Title: Clinical features, disease progression, and nuclear imaging in ATXN2-related parkinsonism in a longitudinal cohort. Structured and disordered regions of Ataxin-2 …
6311 - Gene ResultATXN2 ataxin 2 [ (human)] - National Center for ...
ATXN2 CAG expansion is the sole causative mutation responsible for parkinsonian phenotype of spinocerebellar ataxia-2. results indicate presence of intermediate CAG repeat expansion in …
ATXN2人源基因|ATXN2基因突变_致病性_靶点-RDDC官网
这个基因属于一组与微卫星扩张疾病相关的基因，这类神经系统和神经肌肉疾病是由短重复DNA片段扩张引起的。 这个基因编码的蛋白质在N端附近有两个球形结构域，其中一个含有氯素介导 …