2024年12月24日 · ACAA2 (Acetyl-CoA Acyltransferase 2) is a Protein Coding gene. Diseases associated with ACAA2 include Disorder Of Keton Body Transport and Lipid Metabolism Disorder. Among its related pathways are Fatty acid metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include RNA binding and acetyl-CoA C-acyltransferase activity.

Acetyl-Coenzyme A acyltransferase 2 is an acetyl-CoA C-acyltransferase enzyme. The ACAA2 gene encodes a 41.9 kDa protein that is composed of 397 amino acids and contains 88 observed peptides. [7][8] The encoded protein catalyzes the last step of …

The acetyl CoA acyltransferase 2 (ACAA2) is a key enzyme of the fatty acid oxidation pathway, catalyzing the last step of the mitochondrial beta oxidation, thus playing an important role in the fatty acid metabolism. The purpose of this study was to …

Broad expression in liver (RPKM 207.5), kidney (RPKM 133.1) and 19 other tissues. 编码的蛋白质催化线粒体脂肪酸 β-氧化螺旋的最后一步。 与大多数线粒体基质蛋白不同，它包含不可切割的氨基末端靶向信号。 [RefSeq 提供，2008 年 7 月] The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral.

2025年2月9日 · ACAA2 is a functional BNIP3 binding partner and provide a possible linkage between fatty acid metabolism and apoptosis of cells. The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral.

2023年10月5日 · ACAA2, also known as 3-ketoacyl-CoA thiolase, is a rate-limiting enzyme in the mitochondria that is responsible for catalysing the last step of the mitochondrial beta-oxidation pathway [27, 28,...

Acetyl-CoAacyltransferase2 (ACAA2) is a key enzyme in the fatty acid oxidation pathway that catalyzes the final step of mitochondrial β oxidation, which plays an important role in fatty acid metabolism. The expression of ACAA2 is closely related to the occurrence and malignant progression of tumors. …

2024年11月3日 · Clinical resource with information about ACAA2, A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus., Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans., and available tests.

2023年1月1日 · ACSS2 is a bidirectional enzyme that can decompose acetyl-CoA to produce acetate when acetyl-CoA levels are excessive, thereby achieving a steady state of acetyl-CoA. PDC is found in the mitochondria and nucleus. PDC in mitochondria converts pyruvate to acetyl-CoA, which participates in TCA cycle.

2024年4月24日 · Acetyl-CoAacyltransferase2 (ACAA2) is a key enzyme in the fatty acid oxidation pathway that catalyzes the final step of mitochondrial β oxidation, which plays an important role in fatty acid metabolism. The expression of ACAA2 is closely related to the occurrence and malignant progression of tumors.