
ACSL3 Gene - GeneCards | ACSL3 Protein | ACSL3 Antibody
2024年12月24日 · ACSL3 (Acyl-CoA Synthetase Long Chain Family Member 3) is a Protein Coding gene. Diseases associated with ACSL3 include Intellectual Developmental Disorder, …
ACSL3 - Wikipedia
Long-chain-fatty-acid—CoA ligase 3 is an enzyme that in humans is encoded by the ACSL3 gene. [5] The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A …
文献分享丨Mol Cell铁死亡与脂质代谢和细胞信号转导 - 知乎
acsl3和acsl4酶被证明可以调节pls和铁死亡的敏感性组成,因为它们分别对mufas和pufas具有明显的底物偏好。 激活的FAs通过两条不同的途径被整合到甘油主链的sn-2位置:从头合成途径和 …
ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
2022年11月29日 · The long-chain fatty acyl CoA synthetase (ACSLs) family of enzymes contributes significantly to lipid metabolism and produces acyl-coenzyme A by catalyzing fatty …
ACSL3 is an unfavorable prognostic marker in cholangiocarcinoma ...
2024年12月20日 · We identified acyl-CoA synthetase long chain family member 3 (ACSL3) as a potential ferroptosis suppressor in high-risk CCA patients. Using a panel of CCA cell lines, we …
ACSL3 regulates lipid droplet biogenesis and ferroptosis
2022年10月3日 · ACSL3 regulates the accumulation of lipid droplets in ccRCC and is essential for tumor growth. In addition, ACSL3 also modulates ferroptosis sensitivity in a manner dependent …
Targeting ACSLs to modulate ferroptosis and cancer immunity
2024年10月17日 · ACSL3 facilitates the conversion of OA into OA-CoA, which membrane bound O-acyltransferase domain containing 1 (MBOAT1) and MBOAT2 then catalyze for integration …
酰基辅酶 A 合成酶长链家族成员 3(ACSL3)基因 | MCE
该基因编码的蛋白质是长链脂肪酸辅酶 A 连接酶家族的一种同工酶。 尽管底物特异性、亚细胞定位和组织分布不同,但该家族的所有同工酶都将游离的长链脂肪酸转化为脂肪酰基辅酶 A …
ACSL3基因研究现状 - 百度学术
长链酰基辅酶A合成酶3 (ACSL3)基因是长链酰基辅酶A合成酶 (ACSLs)家族成员之一,ACSL3能促进卵磷脂的合成和细胞内脂滴形成,参与脂肪酸氧化和维持脂滴形成的两种代谢途径,ACSL3基 …
脂酰辅酶A长链合成酶3及其相关疾病 - pku.edu.cn
本文基于国内外对ACSL3的研究,对该基因的结构、在细胞脂代谢中的作用机制及其相关疾病进行归纳,进一步探究ACSL3在脂滴的合成、自噬、铁死亡过程中的作用,为防治动脉粥样硬化、 …