Ad-Cre (Cre Recombinase Adenovirus) - SignaGen
Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals. This pre-packaged adenovirus …
条件性敲除小鼠的原理、构建与应用 - 知乎 - 知乎专栏
Cre-Lox基因重组系统是一种被广泛应用于特异性基因敲除、基因易位、基因翻转以及基因插入等操作的基因重组手段。 Cre重组酶 （cyclization recombination enzyme）最早于1981年在P1 …
肺癌模型 (原位/转移) 构建大全 - 王进的个人网站
2020年6月6日 · Ras在人类肿瘤频发突变，K-ras的激活突变是肺部肿瘤产生的原因之一。在k-ras locus上敲入了Lox-Stop-Lox-Kras G12D ，通过小鼠鼻腔注入Ad-Cre重组腺病毒，诱导肺中 …
Ad-Cre-GFP (Cre recombinase adenovirus co-expression with …
Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals. This adenovirus expresses Cre …
Adenovirus Cre (Cre Recombinase Adenovirus) - LifeSct
Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals. This pre-packaged adenovirus …
AAV在肺脏中的特异性基因调控策略 - hanbio.net
本文将结合相关研究案例详细介绍肺组织靶向性AAV的选择，包括血清型、特异性启动子以及肺组织感染的注射方式等，希望能够为相关研究的科研工作者们提供一些思路和帮助。 三、肺嗜 …
Conditional mouse lung cancer models using adenoviral or …
2009年6月25日 · To generate tumors sporadically in the lungs of K-ras LSL-G12D/+ mice, our laboratory initially used replication-deficient adenoviruses expressing Cre (Ad-Cre) to deliver …
如何利用「Cre/loxp」实现条件性基因编辑？ - 知乎
Cre 重组酶(Cyclization Recombination Enzyme, 即环化重组酶)，是细菌噬菌体P1的I型拓扑异构酶。其基因编码区序列全长1029bp，为38kDa大小的、由343个氨基酸组成的多肽单体蛋白 …
Ad CMV Cre - Kerafast
Ad Cre expresses Cre under control of a CMV promoter. Ready-made control adenoviruses (Ad) are generally in stock and can ship anytime. These particles are CsCl purified and supplied in …
Cre-loxP 重组是一种特定位点的重组酶技术，可在DNA的特定位点上执行删除、插入、易位及倒位， 用该系统可以针对特定的细胞类型或采用特定的外部刺激，对细胞中 DNA 进行修改。
- 某些结果已被删除