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    Nature
    https://www.nature.com › articles

    Adipogenesis and metabolic health | Nature Reviews Molecular …

    • Obesity is characterized by increased adipose tissue mass and has been associated with a strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public health issue of major prop… 展开

    Introduction

    Overnutrition is currently one of the most costly challenges for public health. The increasing prevalence of obesity sparked great interest in understanding the physiological me… 展开

    Nature
    Physiological roles of white adipocytes

    The defining feature of adipocytes is their ability to store excess calories in the form of triglycerides, which are packaged into large lipid droplets that take up most of the cell. Storing energy a… 展开

    Nature
    Molecular mechanisms of adipogenesis

    Adipogenesis is the process whereby fibroblast-like progenitor cells (Box 2) restrict their fate to the adipogenic lineage, accumulate nutrients and become triglyceride-filled … 展开

    Nature
    Sites of adipogenesis

    It is helpful to consider adipose tissue as divided into subcutaneous (localized beneath the skin) and visceral (distributed in the abdominal cavity) depots or fat pads. In humans, the p… 展开

    Nature
    Why do adipose progenitor cells give rise to swats during adipogenesis?
    Fig. 1: Human adipose progenitor cells give rise to SWATs during adipogenesis to maintain the progenitor pool. Adipose progenitor cells (APCs) are adult stem cells in the adipose tissue stroma. Upon activation of adipogenesis, APCs undergo active proliferation and differentiation to generate mature, functional adipocytes.
    nature.com