We subsequently showed that AI-based workflow (AI-PTEN) could reliably detect PTEN loss in prostate cancer tissue cores, offering a streamlined objective biomarker assessment system 20.

2023年10月1日 · AI-PTEN showed high sensitivity (86%) and specificity (86%) for detecting PTEN loss compared with cPTEN as a reference on the core level (Supplementary Table S2) and AI …

2025年2月21日 · 研究人员们巧妙地利用荧光共振能量转移（FRET, Fluorescence resonance energy transfer）原理，将PTEN蛋白改造为构象敏感的"分子探针"。 通过在其N端和C端分别标 …

Phosphatase and tensin homolog (PTEN) loss is associated with adverse outcomes in prostate cancer and can be measured via immunohistochemistry. The purpose of the study was to …

2020年9月3日 · Phosphatase and tensin homolog (PTEN) loss is associated with adverse outcomes in prostate cancer and has clinical potential as a prognostic biomarker. The …

Phosphatase and tensin homolog (PTEN) loss associates to adverse outcomes in prostate cancer and can be measured via immunohistochemistry (IHC). The purpose of the study was to …

Phosphatase and tensin homolog (PTEN) loss is associated with adverse outcomes in prostate cancer and has clinical potential as a prognostic biomarker. The objective of this work was to …

通过病理学家常规视觉评分 （cpten） 和基于 ai 的自动图像分析管道 （ai-pten） 独立评估来自金丝雀基金会 （n = 1264） 的术后组织微阵列切片，用抗 pten 抗体染色。

2023年6月1日 · This study demonstrates the clinical value of an affordable and fully automated AI-powered PTEN assessment for evaluating the risk of developing metastasis or disease …

PTEN是迄今发现的第一个具有双重特性磷酸酶活性的肿瘤抑制基因，有 脂质磷酸酶 和 蛋白磷酸酶 双重特异性，在细胞内多条信号传导途径调控中起着重要作用，自发现以来受到众多学者 …