5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate. AICAR is an analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. The drug has also been shown as a potential treatment for diabetes by increasing the metabolic ...

AICAR (Acadesine) 是一种腺苷类似物，也是一种 AMPK 激活剂。 AICAR 调节葡萄糖和脂质的代谢，并抑制促炎细胞因子和 iNOS 的产生。 AICAR 也是一种自噬 (autophagy)， YAP 和 mitophagy 抑制剂。 MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务. 1. 客户 无需 承担相应的运输费用。 2. 同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内. 可免费申领 三个不同产品 的试用装。 3. 试用装只面向 终端客户 …

aicar AMPK是代谢调控的关键蛋白，当能量供应不足时，AMP/ATP的比率上调，AMPK就会被激活，抑制合成代谢。 在细胞或动物水平，AICAR可以通过激活AMPK从而促进骨骼肌非胰岛素依赖的葡萄糖摄入。

2024年2月9日 · AICAR is an analog of adenosine monophosphate, and has been documented to: Our research team has put together this AICAR dosage calculator and guide to go over the peptide’s possible research applications and side effects. Read through the end as we reveal our go-to online source for buying research-grade peptides, including AICAR.

5-Aminoimidazole-4-carboxamide ribonucleoside (AICAr) has been one of the most commonly used pharmacological modulators of AMPK activity. The majority of early studies on the role of AMPK, both in the physiological regulation of metabolism and in cancer pathogenesis, were based solely on the use of AICAr as an AMPK-activator.

5-Aminoimidazole-4-carboxamide ribonucleoside (AICAr) has been one of the most commonly used pharmacological modulators of AMPK activity. The majority of early studies on the role of AMPK, both in the physiological regulation of metabolism and in cancer pathogenesis, were based solely on the use of …

Acadesine is an adenosine regulating agent developed by PeriCor Therapeutics and licensed to Schering-Plough in 2007 for phase III studies. The drug is a potential first-in-class agent for prevention of reperfusion injury in CABG surgery. Schering began patient enrollment in phase III studies in May 2009.

AICAR (Acadesine) 是一种 AMP 活化蛋白激酶的细胞渗透激活剂（也是一种 AMPK激活剂）。 被腺苷转运体吸收到细胞中，并被腺苷激酶磷酸化为活性核苷酸 ZMP（5-氨基咪唑-4-甲酰胺核糖核苷），它模拟 AMP 对 AMPK 系…

2019年11月14日 · Here’s what athletes should know about AICAR and other prohibited AMP activated protein kinase activators. What is AICAR? AICAR (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) is a substance produced naturally by the body that stimulates AMP activated protein kinase (AMPK), a protein that regulates metabolism in a variety of ways.

AICAR，全称为5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside，也称AICA Riboside或Acadesine，是一种可通透细胞膜AMP-activated protein kinase(AMPK)的激活剂。AMPK是代谢调控的关键蛋白，当能量供应不足时，AMP/ATP的比率上调，AMPK就会被激活，抑制合成代谢。