
The Bioimaging Story of AIEgens | Chemical & Biomedical Imaging
2023年7月3日 · The boom of aggregate-induced emission luminogens (AIEgens) in the last two decades has revolutionized the design strategy of luminescent materials for biological applications. This Review summarizes the advantages …
AIEgens: An emerging fluorescent sensing tool to aid food ... - PubMed
In this contribution, we review the latest developments of food safety monitoring by AIEgens, which will focus on the molecular design of AIEgens and their sensing principles. Several examples of AIE-based sensing applications for screening food contaminations are highlighted, and future perspectives and challenges in this emerging field are ...
AIEgens: Next Generation Signaling Source for Immunoassays?
2022年11月8日 · Luminogens with aggregation-induced emission (AIEgens) properties have numerous broad applications in fields of chemical and biological analyses due to their exceptional photostability, excellent signal reliability, high quantum yield, and large Stokes’ shift.
Aggregation-induced emission luminogens for image-guided …
2021年11月10日 · Specifically, the folic conjugated-AIE luminogen (folic-AIEgen) generates strong and stable fluorescence for the detection and surgical excision of sentinel lymph nodes (SLNs).
Molecular Design and Biomedical Application of AIEgens with ...
2023年5月19日 · We extensively describe the photoresponsive AIEgens containing DPE groups as the photoisomerization/photocyclization units, and then, we highlight the most typical and promising applications of these AIEgens in the biomedical field.
Integration of AIEgens into covalent organic frameworks for …
2023年9月2日 · Here we show the construction of a covalent organic framework (COF-919) from planar and twisted AIEgen-based motifs as a dual-inducer of pyroptosis and ferroptosis for efficient antitumor...
Cationic AIEgens with large rigid π-planes: Specific bacterial …
Outline schematic of the use of AIEgens for bacterial imaging and the process of killing bacteria and promoting wound healing. (a) Application of these molecules in imaging discrimination between G(+) (Gram-positive bacteria) bacteria (spherical) and G(−) bacteria (clubbed); (b and c) bactericidal mechanism of AIEgens; (d) Procedure of ...
AIEgens for microorganism-related visualization and therapy
2023年1月21日 · Luminogens with aggregation-induced emission properties are now recognized as potent fluorescent agents for the diagnosis and treatment of microorganisms. In this review, we summarized the most recent developments of AIEgen-based biomaterials and discussed the advantages of AIE fluorescent probes for imaging.
AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms
2021年3月8日 · In general, AIEgens refer to those luminogenic chemicals that are nonluminescent in solution, but luminescent in either the aggregated or solid states. This review is focused on the emergence of AIE materials in protein …
Regulating the proximity effect of heterocycle-containing AIEgens …
2023年6月24日 · Unlike planar ACQ molecules, luminogens with AIE effect (AIEgens) show twisted or easily distorted conformation, and the restriction of intramolecular motion (RIM) is proven as the mechanism for...
Aggregation-Induced Emission Luminogens Realizing High …
2025年1月2日 · A revolutionary transformation in biomedical imaging is unfolding with the advent of aggregation-induced emission luminogens (AIEgens). These cutting-edge molecules not only overcome the limitations of traditional fluorescent probes but also improve the boundaries of high-contrast imaging.
Diverse interactions between AIEgens and …
2024年7月11日 · We provide an overview of novel strategies to enable AIEgens to interact with biomolecules and organisms, both in vitro and in vivo, focusing on their potential applications in disease diagnosis and precision treatment.
AIEgens: Next Generation Signaling Source for Immunoassays?
2022年11月25日 · Luminogens with aggregation-induced emission (AIEgens) properties have numerous broad applications in fields of chemical and biological analyses due to their exceptional photostability, excellent signal reliability, high quantum yield, and large Stokes' shift.
AIEgens for microbial detection and antimicrobial therapy
Recently, luminogens with aggregation-induced emission characteristics (AIEgens) have emerged as powerful fluorescent tools for microbial detection and antimicrobial therapy. In this review, we highlighted the latest advancements of AIEgen-based biofunctional materials and systems in …
AIE luminogens: emission brightened by aggregation
2015年9月1日 · Luminogens with the feature of aggregation-induced emission (AIE) are a class of ‘heterodox’ molecules, whose emissions are brightened by aggregate formation. The restriction of their intramolecular motions in an aggregate state is the main cause of the AIE process.
Recent Advances in AIEgens for Metal Ion Biosensing and Bioimaging …
2019年12月16日 · A variety of AIE fluorogens (AIEgens) have been developed in the past decades for tracing metal ions. This review highlights recent advances (since 2015) in AIE-based sensors for detecting metal ions in biological systems.
Nonlight-Driven Aggregation-Induced Emission Luminogens for …
2025年3月4日 · In this Review, we devote attention to the fundamental background of combining chemical energy, ultrasound, and X-ray sources with AIEgens, highlighting recent progress in unconventional activation methods for AIEgens in bioimaging and theranostics.
Microfluidic systems for infectious disease diagnostics
2024年2月19日 · Our review offers an opportunity to explore recent research trends and emerging technologies in the field of microfluidic systems enabling rapid and sensitive detection of pathogens or biomarkers associated with infectious diseases.
AIEgens for Bacterial Imaging and Ablation - PubMed
This review summarizes the recent advances in AIEgens for the diagnosis and treatment of pathogen infections. Special attention has been paid to the molecular design, the application in bacterial imaging and ablation in vitro and in vivo, and the biocompatibility of AIEgens.
Polycyclic Aromatic Hydrocarbons in China: Will Decoupling of …
2022年1月6日 · Polycyclic aromatic hydrocarbons (PAHs) are emitted into the environment by daily anthropogenic activities and they potentially threaten human health. Over the past 40 years, the coupling between PAHs emissions driven by energy transition and socioeconomic factors has yet to be determined, and future trends between the two parameters are unclear.