As the name says, “Ayuda sa Kapos ang Kita Program” (AKAP) provides financial aid to minimum wage earners falling under the low-income category, who are severely affected by rising inflation. The main legal basis of AKAP is the “General Appropriations Act of 2024, Special Provision No.3, DSWD Budget,” which authorized the funding for the program.

2024年11月12日 · Speaker Ferdinand Martin G. Romualdez assisted by Quezon City Rep. Franz Pumaren spearheaded the distribution of Ayuda Para sa Kapos ang Kita Program (AKAP) to 13,632 beneficiaries consisting largely of SM North employees at SM North Edsa in Quezon City Tuesday afternoon.

A型激酶锚定蛋白 (A-kinase anchoring proteins，AKAPs)是一类结构不同而功能相关的蛋白家族，其主要功能是将cAMP依赖性蛋白激酶A（PKA）锚定于特定的亚细胞结构.PKA是第二信使cAMP的主要效应器，而AKAPs在靶向定位和调节PKA介导的磷酸化事件方面扮演重要角色....

2004年12月1日 · Here, we discuss two emerging principles in AKAP signalling: the combinatorial assembly of different enzymes on the same AKAP backbone; and the dynamic reorganization of AKAP complexes. cAMP...

2025年1月2日 · MANILA – The first year implementation of the Department of Social Welfare and Development’s (DSWD) Ayuda para sa Kapos ang Kita Program (AKAP) was very successful, having demonstrated a strong impact on many near-poor Filipinos, the agency’s spokesperson Irene Dumlao said on Thursday.…

AKAP targeting concentrates PKA at distinct subcellular locations near sources of cAMP, including the plasma membrane at ion channels and receptors, the Golgi apparatus, the mitochondria (outer membrane and intermembrane space), the centrosome, specific regions within active cytoskeletal machinery, vesicles, and others (Figure 2A,B and Table 1).

AKAP QC INC. 592 likes. Ang Official Page ng Asosasyon ng mga Barangay Kagawad sa Pangatlong Distrito ng Quezon City

2024年11月22日 · LEGAZPI, Albay — House Speaker Ferdinand Martin Romualdez has urged “some senators” opposing the Ayuda sa Kapos ang Kita Program (AKAP) to talk to the people so that they would understand its significance.

2022年1月1日 · A-kinase anchoring protein (AKAP) interaction with cAMP-dependent protein kinase (PKA). The unifying characteristic of canonical AKAPs is the presence of a structurally conserved amphipathic binding helix (orange) which binds in a hydrophobic cleft created by the docking and dimerization (D/D) domains of the regulatory (R) subunits of PKA.

In summary, the novel hydrocarbon-stapled peptides developed in this study represent a new class of AKAP disruptors to study compartmentalized RII-regulated PKA signaling in cells. A 激酶锚定蛋白 (AKAP) 通过支撑关键的细胞内信号复合物在蛋白激酶 A (PKA) 的空间和时间调节中发挥重要作用。 在这里，我们报告了构象受限肽的设计，这些肽以异构体选择性方式破坏 PKA 和 AKAP 之间的相互作用。