AKR1C2 Gene - GeneCards | AK1C2 Protein | AK1C2 Antibody
2024年12月24日 · AKR1C2 (Aldo-Keto Reductase Family 1 Member C2) is a Protein Coding gene. Diseases associated with AKR1C2 include 46,Xy Sex Reversal 8 and Cic-Rearranged …
AKR1C2 - Wikipedia
Aldo-keto reductases, including AKR1C2, are NAD(P)H-linked oxidoreductases that primarily catalyze the reduction of aldehydes and ketones to primary and secondary alcohols. This …
AKR1C2 在人类癌症中的功能、耐药性和预后作用。,Neoplasma
研究表明AKR1C2参与调节肿瘤侵袭、迁移等恶性表型，消除活性氧（ROS），促进肿瘤细胞化疗耐药，在某些癌症中具有预后价值。 在这里，我们重点讨论AKR1C2在不同类型肿瘤中的作用 …
Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, and ...
AKR1C2, is also known as bile-acid binding protein and DD2, has lower catalytic efficiencies but preferentially reduces 3-ketosteroids. AKR1C2 preferentially reduces DHT to the weak …
AKR1C2 aldo-keto reductase family 1 member C2 [ (human)]
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway. Ligand entry in human ileal bile acid-binding protein is mediated …
Function, drug resistance and prognostic effect of AKR1C2 in …
Studies have shown that AKR1C2 is involved in regulating tumor invasion, migration, and other malignant phenotypes, eliminating reactive oxygen species (ROS), promoting chemotherapy …
醛酮还原酶家族 1 成员 C2（AKR1C2）基因 | MCE
该基因编码醛/酮还原酶超家族的一个成员，该家族由 40 多种已知的酶和蛋白质组成。 这些酶使用 NADH 和/或 NADPH 作为辅因子催化醛和酮转化为其相应的醇。 这些酶显示重叠但不同的底物 …
醛酮还原酶1C2在肿瘤中的研究进展-期刊-万方数据知识服务平台
2023年9月7日 · 醛酮还原酶1C2 (AKR1C2)是一种依赖还原型辅酶Ⅱ (NADPH)将醛和酮的羟基还原为相应的醇的醛酮还原酶 (AKRs),其具备3-α-羟基类固醇脱氢酶活性,能够以高亲和力结合胆汁 …
AKR1C2 - 药物、适应症、专利 - 智慧芽新药情报库
Here we report PFOA inhibition of AKR family 1 member C2 (AKR1C2), leading to dysregulation of androgen action. Spectrofluorimetric inhibitor screens identified PFOA as a competitive and …
Human Gene AKR1C2 (ENST00000380753.9) from GENCODE V46
Description: Homo sapiens aldo-keto reductase family 1 member C2 (AKR1C2), transcript variant 2, mRNA. (from RefSeq NM_205845) RefSeq Summary (NM_205845): This gene encodes a …