Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 (4) and by phosphorylation within the carboxy terminus at Ser473. The previously elusive …

AKT is a serine/threonine kinase and it participates in the key role of the PI3K signaling pathway. Phosphatidylinositol-3 kinase (PI3K) is the key regulator of AKT activation. The recruitment of …

2012年12月1日 · Akt is a 56-kDa member of the AGC serine/threonine protein kinase family, discovered in 1991 [1], [2]. In mammals, there are three genes, located on different …

2024年11月29日 · Akt, also known as protein kinase B (PKB), is a 57-kDa integral kinase and signaling node that belongs to the protein kinase A, kinase G, and kinase C (AGC) superfamily …

丝氨酸-苏氨酸激酶 Akt（也称为蛋白激酶 B（PKB））在广泛影响的信号网络中起着关键作用。Akt 激活通过下游靶标和相互作用伙伴产生多种细胞内反应，从而成为细胞信号传导通路的主开关 …

Explore the Akt pathway that mediates apoptosis and cell proliferation. Find antibodies to detect target proteins, including Akt, p70 S6K, CREB, and p53.

Since its initial discovery as a proto-oncogene, the serine/threonine kinase Akt (also known as protein kinase B or PKB) has become a major focus of attention because of its critical …

探索介导细胞凋亡和细胞增殖的 Akt 通路。查找检测靶蛋白的抗体，包括 Akt、p70 S6K、CREB 和 p53。