Acute megakaryoblastic leukemia (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally and injure various tissues.

急性巨核细胞白血病（acute megakaryocytic leukemia，AMKL）是急性髓系白血病（acute myeloid leukemia，AML）的一个亚型，FAB分型为AML-M7型 [1]，约占儿童AML 5%~15% [2 …

2024年11月5日 · This study presents updated clinicopathologic data from a large, pooled cohort of patients with AMKL. It identifies age, presence of Down's Syndrome, occurrence in the …

Acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) that affects megakaryocytes. It is generally subdivided into three groups based on the …

2023年11月2日 · The cytogenetic abnormality t (1;22) (p13.3;q13.1), has been reported in children with non-DS AMKL, which involves the fusion of RNA-binding motif protein-15 and …

Acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) in which cells morphologically resemble abnormal megakaryoblasts. While rare in adults, AMKL …

Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia (AML) in which leukemic blasts have megakaryocytic features. AMKL makes up 4%–15% of newly …

AMKL的亟需通过骨髓细胞形态学联合细胞化学及组织病理学、完整的流式免疫分型检测、细胞遗传学 (染色体核型分析、荧光原位杂交FISH)、分子生物学检测及电镜技术等综合辅助其诊断 …

2023年11月10日 · 急性巨核细胞白血病（M7、AMKL），乃由毒害因子激发了机体造血组织中巨核细胞系统造血中枢，使其异常增生而引起的一种出血性恶性疾病。 正常巨核细胞的胞体较 …

2017年1月1日 · AMKL is a subtype of acute myeloid leukemia (AML). The biologic features of AMKL are heterogeneous, and the ongoing characterization of the disease pathogenesis is …