Androgen receptor - Wikipedia
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor [9] that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone, [10] in the cytoplasm and then translocating into the nucleus.
Androgen Receptor Structure, Function and Biology: From Bench …
The actions of androgens such as testosterone and dihydrotestosterone are mediated via the androgen receptor (AR), a ligand-dependent nuclear transcription factor and member of the steroid hormone nuclear receptor family.
Androgen Physiology: Receptor and Metabolic Disorders
2021年7月2日 · The biological actions of testosterone and DHT are mediated by the androgen receptor, a member of the nuclear receptor superfamily, which in response to hormone regulates gene expression in target tissues.
The Roles of Androgens in Humans: Biology, Metabolic Regulation …
The androgen receptor (AR) is a classical nuclear receptor, primarily acting through the selective induction of the translation of DNA strands to eventually synthetize specific proteins. The AR elicits the expression of a number of genes depending on the target cells and the modulation of …
Androgen Receptor - an overview | ScienceDirect Topics
An androgen receptor (AR) is a ligand-dependent nuclear transcription factor that mediates the action of androgens in the body, playing a crucial role in male sexual differentiation and physiology. You might find these chapters and articles relevant to this topic.
Chemistry and Structural Biology of Androgen Receptor - PMC
Androgen receptor (AR) is a member of the steroid and nuclear receptor superfamily, 1 which is composed of over 100 members and continues to grow. Among this large family of proteins, only five vertebrate steroid receptors—estrogen, progesterone, androgen, glucocorticoid, and mineralocorticoid receptors—are known.
Androgen Receptor Structure, Function and Biology: From Bench …
The actions of androgens such as testosterone and dihydrotestosterone are mediated via the androgen receptor (AR), a ligand-dependent nuclear transcription factor and member of the steroid hormone nuclear receptor family. Given its widespread expression in many cells and tissues, the AR has a divers …
AR gene - MedlinePlus
The AR gene provides instructions for making a protein called an androgen receptor. Androgens are hormones (such as testosterone) that are important for normal male sexual development before birth and during puberty. Androgen receptors allow the body to respond appropriately to these hormones.
Mechanism of androgen receptor action - ScienceDirect
2009年6月20日 · Recent research provides a much more detailed understanding of the role of the androgen receptor in normal human development and physiology, its structure, and its functioning. This review discusses genomic and non-genomic actions of the androgen receptor, as well as their co-regulators.
Androgen Receptor - an overview | ScienceDirect Topics
The androgen receptor is a steroid hormone nuclear receptor that contains three principal functional domains: an N-terminus domain that interacts with components of the transcriptional regulatory apparatus, a central DNA-binding domain, and a C-terminus ligand-binding domain.