Most of the ANGPTLs exhibit multibiological properties, including established functional roles in lipid and glucose metabolism, inflammation, hematopoiesis, and cancer. This report …

ANGPTL（Angiopoietin-like proteins，血管生成素样蛋白）家族包括8个成员，是分泌型糖蛋白，具有3个保守的结构域，即N端的信号肽、coiled-coil结构域（CCD）和C端fibrinogen-like结 …

In this review, we summarize the fundamental roles of ANGPTL4 in regulating metabolic and nonmetabolic functions and their implication in lipid metabolism and with several aspects of …

2024年12月24日 · ANGPTL4 (Angiopoietin Like 4) is a Protein Coding gene. Diseases associated with ANGPTL4 include Plasma Triglyceride Level Quantitative Trait Locus and Familial …

In this review, we summarize the fundamental roles of ANGPTL4 in regulating metabolic and non-metabolic functions and their implication lipid metabolism and with several aspects vascular …

2014年1月23日 · Angiopoietin-like proteins (ANGPTLs) are a family of proteins structurally similar to the angiopoietins. To date, eight ANGPTLs have been discovered, namely ANGPTL1 to …

2014年1月22日 · Angiopoietin-like proteins (ANGPTLs) are a family of proteins structurally similar to the angiopoietins. To date, eight ANGPTLs have been discovered, namely ANGPTL1 to …

Angiopoietin-like protein (ANGPTL)3 regulates plasma lipids by inhibiting LPL and endothelial lipase (EL). ANGPTL3 inactivation lowers LDL-C independently of the classical LDLR …

2023年12月1日 · After 2 decades of research, new therapeutic targets, such as angiopoietin-like proteins (ANGPTLs), are emerging. ANGPTLs belong to a family of 8 members, from …

2017年7月20日 · Loss-of-function variants in the angiopoietin-like 3 gene (ANGPTL3) have been associated with decreased plasma levels of triglycerides, low-density lipoprotein (LDL) …