
Angiopoietin-Like Proteins: A Comprehensive Look - PMC
Most of the ANGPTLs exhibit multibiological properties, including established functional roles in lipid and glucose metabolism, inflammation, hematopoiesis, and cancer. This report …
新一代降脂药物靶点-ANGPTLs - 知乎 - 知乎专栏
ANGPTL(Angiopoietin-like proteins,血管生成素样蛋白)家族包括8个成员,是分泌型糖蛋白,具有3个保守的结构域,即N端的信号肽、coiled-coil结构域(CCD)和C端fibrinogen-like结 …
ANGPTL4: a multifunctional protein involved in metabolism and ... - PubMed
In this review, we summarize the fundamental roles of ANGPTL4 in regulating metabolic and nonmetabolic functions and their implication in lipid metabolism and with several aspects of …
ANGPTL4 Gene - GeneCards | ANGL4 Protein | ANGL4 Antibody
2024年12月24日 · ANGPTL4 (Angiopoietin Like 4) is a Protein Coding gene. Diseases associated with ANGPTL4 include Plasma Triglyceride Level Quantitative Trait Locus and Familial …
ANGPTL4, A MULTIFUNCTIONAL PROTEIN INVOLVED IN …
In this review, we summarize the fundamental roles of ANGPTL4 in regulating metabolic and non-metabolic functions and their implication lipid metabolism and with several aspects vascular …
Angiopoietin-like proteins: a comprehensive look - PubMed
2014年1月23日 · Angiopoietin-like proteins (ANGPTLs) are a family of proteins structurally similar to the angiopoietins. To date, eight ANGPTLs have been discovered, namely ANGPTL1 to …
Angiopoietin-Like Proteins: A Comprehensive Look - Frontiers
2014年1月22日 · Angiopoietin-like proteins (ANGPTLs) are a family of proteins structurally similar to the angiopoietins. To date, eight ANGPTLs have been discovered, namely ANGPTL1 to …
Angiopoietin-like protein 3 governs LDL-cholesterol levels ... - PubMed
Angiopoietin-like protein (ANGPTL)3 regulates plasma lipids by inhibiting LPL and endothelial lipase (EL). ANGPTL3 inactivation lowers LDL-C independently of the classical LDLR …
Angiopoietin-Like Proteins: Cardiovascular Biology and …
2023年12月1日 · After 2 decades of research, new therapeutic targets, such as angiopoietin-like proteins (ANGPTLs), are emerging. ANGPTLs belong to a family of 8 members, from …
Genetic and Pharmacologic Inactivation of ANGPTL3 and …
2017年7月20日 · Loss-of-function variants in the angiopoietin-like 3 gene (ANGPTL3) have been associated with decreased plasma levels of triglycerides, low-density lipoprotein (LDL) …
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