
APOA4 - Wikipedia
The primary translation product of the APOA4 gene is a 396-residue preprotein, which undergoes proteolytic processing to yield apo A-IV, a 376-residue mature O-linked glycoprotein. In most mammals, including humans, apo A-IV synthesis is confined to the …
载脂蛋白(Apolipoprotein) - 知乎 - 知乎专栏
apol-iv, apoliv 这个基因编码载脂蛋白L家族的一个成员。 编码的蛋白质可能在全身的脂质交换和转运中起作用,也可能在胆固醇从外周细胞向肝脏的逆向转运中起作用。
Apolipoprotein A-IV: A Multifunctional Protein Involved in …
Apolipoprotein A-IV (apoA-IV) is a lipid-binding protein, which is primarily synthesized in the small intestine, packaged into chylomicrons, and secreted into intestinal lymph during fat absorption. In the circulation, apoA-IV is present on chylomicron remnants, high-density lipoproteins, and also in …
ApoA-IV: current and emerging roles in intestinal lipid …
Apolipoprotein A-IV (apoA-IV) is secreted by the small intestine on chylomicrons into intestinal lymph in response to fat absorption. Many physiological functions have been ascribed to apoA-IV, including a role in chylomicron assembly and lipid ...
Apolipoprotein A-IV: a protein intimately involved in metabolism
2015年8月1日 · ApoA-IV is primarily synthesized by the small intestine, attached to chylomicrons by enterocytes, and secreted into intestinal lymph during fat absorption. In circulation, apoA-IV is associated with HDL and chylomicron remnants, but a large portion is lipoprotein free.
Apolipoprotein A-IV: a protein intimately involved in metabolism
ApoA-IV was discovered 40 years ago as a major protein component of chylomicrons in postprandial lymph and plasma of both humans and rats (1–3). In plasma it is found on chylomicrons and on HDL, but 40–50% circulates lipid free (1–3). The presence of apoA-IV in the blood is uniquely linked to the absorption and secretion of dietary lipid.
Apolipoprotein A-IV: A Multifunctional Protein Involved in
2019年4月5日 · Apolipoprotein A-IV (apoA-IV) is a lipid-binding protein, which is primarily synthesized in the small intestine, packaged into chylomicrons, and secreted into intestinal lymph during fat absorption. In the circulation, apoA-IV is present on chylomicron remnants, high-density lipoproteins, and also i …
J Intern Med:apoA-IV与肾脏功能那些事 - MedSci.cn
载脂蛋白A-IV(apoA-IV)是一种能抗动脉硬化、抗氧化的糖蛋白。 目前对于该标志物的研究发现,血浆apoA-IV水平升高主要见于慢性肾脏疾病(CKD)或肾功能衰竭患者。
Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis
2018年9月6日 · Here we show that apolipoprotein A-IV (apoA-IV) can be isolated from human blood plasma using platelet β3 integrin-coated beads. Binding of apoA-IV to platelets requires activation of...
Apolipoprotein A-IV: A Multifunctional Protein Involved in ... - MDPI
2019年4月5日 · Apolipoprotein A-IV (apoA-IV) is a lipid-binding protein, which is primarily synthesized in the small intestine, packaged into chylomicrons, and secreted into intestinal lymph during fat absorption. In the circulation, apoA-IV is present on chylomicron remnants, high-density lipoproteins, and also in lipid-free form.