Apolipoprotein E (Apo-E) is a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in Alzheimer's disease and cardiovascular diseases. [5] It is encoded in …

载 脂蛋白 E (apolipoprotein E，ApoE)是一种 多态性 蛋白，参与脂蛋白的转化与代谢过程，其基因可以调节许多生物学功能，与许多眼科疾病发病有关，对ApoE及其 基因多态性 的研究是医学 …

载脂蛋白E （Apolipoprotein E, APOE）是人体一种非常重要的多态性蛋白，是一种含有299个氨基酸的单链多肽糖蛋白，主要存在于 极低密度脂蛋白 （VLDL）、乳糜微粒（CV）和 高密度脂 …

Apolipoprotein (apo) E is a multifunctional protein with central roles in lipid metabolism, neurobiology, and neurodegenerative diseases. It has three major isoforms (apoE2, apoE3, …

Apolipoprotein E (ApoE) is a major cholesterol carrier that supports lipid transport and injury repair in the brain. APOE polymorphic alleles are the main genetic determinants of Alzheimer …

Apolipoprotein (apo) E is a multifunctional protein with central roles in lipid metabolism, neurobiology, and neurodegenerative diseases. It has three major isoforms (apoE2, apoE3, …

在过去三十年里， 载脂蛋白E （Apolipoprotein E, APOE）一直被认为是散发性 阿尔茨海默病 （Alzheimer’s disease, AD）最重要的遗传调控因子，它影响着AD的平均发病年龄和终生患病 …

2019年7月31日 · The apolipoprotein E (APOE) gene has three major allelic variants, APOE*ε2, APOE*ε3 and APOE*ε4; APOE*ε4 is associated with an increased risk and lower age of onset …

Polymorphism in the apolipoprotein E (APOE) gene is a major genetic risk determinant of late-onset Alzheimer disease (AD), with the APOE*ε4 allele conferring an increased risk and the …

Apolipoprotein E (APOE) genotype is the major genetic risk factor for Alzheimer disease (AD); the ε4 allele increases risk and the ε2 allele is protective. In the central nervous system (CNS), …