Dec 24, 2024 · AREG (Amphiregulin) is a Protein Coding gene. Diseases associated with AREG include Ovarian Cystadenoma and Lymphangioma . Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway .

3 days ago · ABERDEEN RENEWABLE ENERGY GROUP (AREG) Established in 2003, AREG is the original energy transition organisation, helping our network of members to access opportunities that accelerate the development and use of …

Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. The biological roles of AREG in the regulation of the epithelial‑mesenchymal transition (EMT) in pancreatic cancer remain unclear.

Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells.

Sep 5, 2024 · Tang and colleagues elucidated the profibrotic role of sustained amphiregulin (AREG) derived from intermediate lung stem cells in driving pulmonary fibrosis and established AREG as a potential disease-severity indicator for idiopathic pulmonary fibrosis.

Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. AREG is synthesized as membrane-anchored pre-protein, and is excreted after proteolytic cleavage, and serves as an autocrine …

The epidermal growth factor (EGF) family member amphiregulin (AREG) was identified 25 years ago in the supernatant of MCF-7 human breast carcinoma cells treated with phorbol 12-myristate 13-acetate (PMA).

Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR) 3 which was observed to be altered in malignant astrocytomas 4-6 and which is responsible for activation of a complex network of pathways, including the …

Feb 9, 2025 · AREG expression is essential for efficient hepatitis C virus assembly and virion release. AREG functions in regulating the invasive breast cancer phenotype, perhaps through altered signaling that occurs when AREG activates plasma membrane localized epidermal growth factor receptor (EGFR).

Jan 1, 2024 · Amphiregulin (AREG) serves as a ligand for the epidermal growth factor receptor (EGFR) and is involved in vital biological functions, including inflammatory responses, tissue regeneration, and immune system function.