We propose that l-arginine can interrupt the vicious cycle that initiates and maintains low NO in hypertension by increasing the formation of NO. 1. l-Arginine is the substrate for vascular nitric …

As a functional amino acid (AA), L-arginine (Arg) serves not only as a building block of protein but also as an essential substrate for the synthesis of nitric oxide (NO), creatine, polyamines, …

Some cell types take up and/or synthesize arginine in support of nitric oxide (NO) synthesis (Fig. 1). In this cycle, arginine is converted to citrulline by nitric oxide synthases (NOS) …

Increasing the arginine availability by arginine therapy or arginase inhibition was therefore proposed as a potential therapy to treat hypertension. Recent studies in septic patients and …

2006年9月1日 · Nitric oxide (NO) is synthesized from l -arginine by NO synthase in virtually all cell types. Emerging evidence shows that NO regulates the metabolism of glucose, fatty acids and …

2004年10月1日 · L-Arginine is the biological precursor of nitric oxide (NO), which serves as an important signal and effector molecule in animals. This review summarizes some structure …

L-Arg is the precursor for the synthesis of nitric oxide (NO); a key signaling molecule via NO synthase (NOS). Endogenous NOS inhibitors such as asymmetric-dimethyl-L-Arg inhibit NO …

NO is produced by all tissues of the body and plays very important roles in the cardiovascular system, immune system and nervous system. NO is formed from L-arginine via the enzyme …

2009年2月25日 · l-Arginine was discovered as a naturally occurring amino acid more than a century ago. 1 The more recent discovery that nitric oxide (NO), 2 derived from l-arginine, is a …

2024年12月1日 · l-arginine generates nitric oxide (NO), a vasodilator that increases blood flow to the brain, providing oxygen and nutrients. It also has anti-inflammatory and anti-apoptotic …