2024年12月24日 · ARMCX3 (Armadillo Repeat Containing X-Linked 3) is a Protein Coding gene. Among its related pathways are Signaling by Rho GTPases and RAC2 GTPase cycle. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is ARMCX1. Regulates mitochondrial aggregation and transport in axons in living neurons.

Armadillo repeat-containing X-linked protein 3 is a protein that in humans is encoded by the ARMCX3 gene. [5] [6] [7] [8]This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression.The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo repeat.Other proteins containing the arm repeat are involved in development ...

ARMCX3 is a novel player in the control of thermogenic adipose tissue plasticity that acts to repress acquisition of the browning phenotype and shows a direct association with indicators of obesity in mice and humans.

2024年12月24日 · Complete information for ARMCX3-AS1 gene (RNA Gene), ARMCX3 Antisense RNA 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium New to GeneCards?

2025年2月8日 · Gene ID: 51566, updated on 8-Feb-2025. This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat.

2022年6月15日 · ARMCX3 is a novel player in the control of thermogenic adipose tissue plasticity that acts to repress acquisition of the browning phenotype and shows a direct association with indicators of...

2024年9月15日 · ARMCX3 knockdown effectively accelerated neural differentiation and controlled inflammatory cytokines at a lower level in hDPSCs in the presence of Pg-LPS. Additionally, knockdown of ARMCX3 notably reduced ROS production and ROS inhibition effectively eliminated the roles of ARMCX3 overexpression in hDPSCs.

2009年5月15日 · We show that ARMCX3 is a mitochondrial outer membrane protein that increases the level of mitochondrially associated Sox10. In addition, we demonstrate that ARMCX3 and Sox10 are co-expressed in the central nervous system as well as in several cell lines and, further, that endogenous ARMCX3 and Sox10 physically associate. Importantly, we …

2016年3月2日 · We show that Armcx3 and Armc10 gain-of-function in vivo results in negative control of progenitor proliferation. Moreover, Armcx3 overexpression induces neuronal differentiation and the settling of postmitotic neurons in the mantle zone.

ARMCX3的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为该基因编码的ALEX家族，其可能在肿瘤抑制中作用的蛋白质的成员。 编码的蛋白含有潜在的N端跨膜结构域和一个犰狳（ARM）重复。 含有臂重复其他蛋白参与发育，组织完整性和肿瘤发生的维护。 该基因与X染色体上的其他家庭成员密切本地化。 编码相同蛋白质三个转录变体已被确定为这个基因。 [由RefSeq的，2008年7月提供]