细胞信号通路详解之AHR信号通路_Per-ARNT-Sim - 搜狐
2019年12月6日 · AHR (Aryl Hydrocarbon Receptor) 是转录调节子bHLH (basic Helix-Loop-Helix)-PAS (Per-ARNT-Sim) 家族的一员，该家族主要调控各种发育和生理功能，包括神经发生、气管 …
The role of DNA-binding and ARNT dimerization on the nucleo
2021年9月14日 · In this study, we have tested whether the sustained nuclear compartmentalization of ligand-bound or basal AHR might further require heterodimerization …
AhR and Arnt differentially regulate NF-κB signaling and …
2014年7月24日 · AhR and Arnt may differentially and independently regulate chemokine-responses induced by both inhaled pollutants and pulmonary infections. Constitutively active, …
The nuclear entry of the aryl hydrocarbon receptor (AHR
2023年11月11日 · The human aryl hydrocarbon receptor (AHR) undergoes continuous shuttling between nucleus and cytoplasm. Binding to exogenous or endogenous ligands promotes its …
AhR signaling pathways and regulatory functions - ScienceDirect
2018年12月1日 · When a ligand crosses the plasma membrane (passive diffusion), it binds to the AhR (the PAS B domain). This allows the translocation of the ligand-receptor complex into the …
AhR and Arnt differentially regulate NF-κB signaling and …
2014年7月24日 · The present study explored the impact of AhR and its binding partner AhR nuclear translocator (Arnt) on p65-activation and two differentially regulated chemokines, …
Structural hierarchy controlling dimerization and target DNA ...
2017年4月10日 · The aryl hydrocarbon receptor (AHR) belongs to the PAS (PER-ARNT-SIM) family transcription factors and mediates broad responses to numerous environmental …
ARNT Gene - GeneCards | ARNT Protein | ARNT Antibody
2024年12月24日 · This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to …
Nat Commun | 武大雷团队揭示银屑病药物本维莫德等配体激活AHR …
2025年2月7日 · 芳香烃受体 （Aryl Hydrocarbon Receptor， AHR） 是一种依赖配体激活的转录因子，广泛表达于人体的免疫系统和皮肤、肠道等屏障器官，是介导微生物与宿主互作的桥梁， …
The regulatory role of ACP5 in the diesel exhaust particle-induced AHR …
2 天之前 · Numerous studies have shown that CYP1A subfamily expression is induced by the activation of the AHR and AHR nuclear translocator (ARNT) as AHR/ARNT heterodimeric …