Aromatase (EC 1.14.14.14), also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1 , a member of the …

Learn more about aromatase inhibitors, including the three types, why they’re used in breast cancer treatment, their side effects, and their benefits.

Aromatase is expressed in multiple tissues, indicating a crucial role for locally produced oestrogens in the differentiation, regulation and normal function of several organs and …

Aromatase is the rate-limiting enzyme in the biosynthesis of estrogens, which play crucial roles on a spectrum of developmental and physiological processes. The biological actions of estrogens …

Aromatase inhibitors (AIs) are drugs used to lower breast cancer risk in some post-menopausal women. For post-menopausal women with a higher-than-average risk of breast cancer, these …

Aromatase is an enzyme that converts androgens into estrogens, and aromatase inhibitors (AIs) can eliminate the production of estrogen. Furthermore, antiestrogens can bind to ER and …

Aromatase catalyzes three separate steroid hydroxylations involved in the conversion of androstenedione to estrone. The first two give rise to 19-hydroxy and 19-aldehyde structures, …