ATPase inhibitor, mitochondrial is an enzyme that in humans is encoded by the ATPIF1 gene. [5][6] This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this …

2016年8月1日 · IF1 bound to the H + -ATP synthase inhibits both the synthase and hydrolase activities. Phosphorylation of S39 of IF1 by mtPKA prevents its binding to the ATP synthase. …

2024年12月24日 · ATP5IF1 (ATP Synthase Inhibitory Factor Subunit 1) is a Protein Coding gene. Diseases associated with ATP5IF1 include Mitochondrial Disease and Fallopian Tube …

2022年5月16日 · We found that inhibitory factor 1 of the mitochondrial FoF1-ATP synthase (ATPIF1), a protein known to inhibit ATP hydrolysis by the reverse function of ATP synthase …

线粒体是真核细胞中动态双层膜结构的细胞器,由外至内可以划分为四个功能区,分别是线粒体外膜 (OMM),线粒体膜间隙,线粒体内膜 (IMM)和线粒体基质.在线粒体内膜上的复合体V (complex V) …

This study aims to understand ATP synthase inhibitory factor 1's (ATPIF1's) role in peripheral nerve regeneration (PNR) using a murine model of sciatic nerve crush injury. Histological …

2021年1月9日 · Overexpression of ATPIF1 contributed to the maintenance of normal structure of mitochondria, inhibiting activation of mitophagy and other signaling proteins (e.g., KLF4 and …

2022年5月16日 · Using ATPIF1 gain- and loss-of-function cell models, we demonstrated that stalled electron flow due to impaired ATP synthase activity triggered mitochondrial ROS …

ATP合酶的活性受抑制因子 (ATPIF1)的调节。 ATPIF1与ATP合酶结合后,对其ATP合成和水解功能进行抑制,从而影响线粒体和细胞内ATP水平。

2025年2月9日 · ATPase inhibitory factor 1 (ATPIF1/IF1) was identified as essential for PARK2 recruitment and mitophagy in cultured cells. The expression of human ATPase inhibitory factor …